Dhapa Nasrin, Alocozy Lamar, Khan Rumana
Sutter Roseville Medical Center, Graduate Medical Education, Roseville, CA 95661, USA.
J Cardiovasc Dev Dis. 2025 May 28;12(6):201. doi: 10.3390/jcdd12060201.
Hypercalcemia is frequently attributed to primary hyperparathyroidism, commonly a result of parathyroid adenomas. Ectopic hyperparathyroidism is characterized by hyperfunctioning parathyroid tissue located outside of expected anatomical locations of endocrine tissue. In this report, we present a rare case of hypercalcemia secondary to a mediastinal ectopic parathyroid adenoma, located between the left atrium and pulmonary artery. Given the unique location of the ectopic gland, diagnosis was delayed with additional complications that followed due to difficulty accessing the gland surgically. Despite this, urgent surgical removal of the ectopic gland allowed for remarkable improvement in presenting symptoms. This clinical case highlights diagnostic and therapeutic challenges that present a unique situation worthy of clinical discussion.
高钙血症常归因于原发性甲状旁腺功能亢进，通常是甲状旁腺腺瘤所致。异位甲状旁腺功能亢进的特征是甲状旁腺组织功能亢进，位于内分泌组织预期解剖位置之外。在本报告中，我们介绍了一例罕见的因纵隔异位甲状旁腺腺瘤继发高钙血症的病例，该腺瘤位于左心房和肺动脉之间。鉴于异位腺体的独特位置，诊断延迟，并因手术难以触及腺体而出现了其他并发症。尽管如此，紧急手术切除异位腺体使症状得到了显著改善。该临床病例突出了诊断和治疗方面的挑战，呈现了一个值得临床讨论的独特情况。
