Horváth Márton, Farkas-Sütő Kristóf, Gyulánczi Flóra Klára, Fábián Alexandra, Lakatos Bálint, Kiss Anna Réka, Grebur Kinga, Gregor Zsófia, Mester Balázs, Kovács Attila, Merkely Béla, Szűcs Andrea
Heart and Vascular Center, Semmelweis University, H-1122 Budapest, Hungary.
J Imaging. 2025 Jun 3;11(6):181. doi: 10.3390/jimaging11060181.
Right ventricular (RV) involvement in left ventricular hypertrabeculation (LVNC) remains under investigation. Due to its complex anatomy, assessing RV function is challenging, but 3D transthoracic echocardiography (3D_TTE) offers valuable insights. We aimed to evaluate volumetric, functional, and strain parameters of both ventricles in LVNC patients with preserved left ventricular ejection fraction (EF) and compare findings to a control group. This study included 37 LVNC patients and 37 age- and sex-matched controls. 3D_TTE recordings were analyzed using TomTec Image Arena (v. 4.7) and reVISION software to assess volumes, EF, and global/segmental strains. RV EF was further divided into longitudinal (LEF), radial (REF), and antero-posterior (AEF) components. LV volumes were significantly higher in the LVNC group, while RV volumes were comparable. EF and strain values were lower in both ventricles in LVNC patients. RV movement analysis showed significantly reduced LEF and REF, whereas AEF remained normal. These findings suggest subclinical RV dysfunction in LVNC, emphasizing the need for follow-up, even with preserved EF.
右心室（RV）受累于左心室致密化不全（LVNC）仍在研究中。由于其解剖结构复杂，评估右心室功能具有挑战性，但三维经胸超声心动图（3D_TTE）提供了有价值的见解。我们旨在评估左心室射血分数（EF）保留的LVNC患者双心室的容积、功能和应变参数，并将结果与对照组进行比较。本研究纳入了37例LVNC患者和37例年龄及性别匹配的对照组。使用TomTec Image Arena（v. 4.7）和reVISION软件分析3D_TTE记录，以评估容积、EF和整体/节段应变。右心室EF进一步分为纵向（LEF）、径向（REF）和前后向（AEF）分量。LVNC组的左心室容积显著更高，而右心室容积相当。LVNC患者双心室的EF和应变值较低。右心室运动分析显示LEF和REF显著降低，而AEF保持正常。这些发现提示LVNC患者存在亚临床右心室功能障碍，强调即使EF保留也需要进行随访。
