Vieira Sofia, Marto Carlos Miguel, Coelho Ana, Amaro Inês, Francisco Inês, Vale Francisco, Paulo Siri, Ferreira Manuel Marques, Carrilho Eunice, Paula Anabela
Faculty of Medicine, Institute of Integrated Clinical Practice, University of Coimbra, 3000-075 Coimbra, Portugal.
Faculty of Medicine, Institute of Experimental Pathology, University of Coimbra, 3000-548 Coimbra, Portugal.
J Funct Biomater. 2025 Jun 4;16(6):210. doi: 10.3390/jfb16060210.
To identify the in vitro techniques used for a microleakage evaluation of restorative materials of coronary structure through a scoping and mapping review.
This scoping review aims to answer the following question: "what methods are currently for the microleakage assessment of coronary restorative materials?"
The Medline, Embase, Cochrane Library, and Web of Science databases were searched to identify relevant studies published between 2020 and 2024. The results obtained were grouped according to the evaluation method, and a narrative synthesis was made.
The literature search identified 1014 articles, and 353 publications were excluded by title and abstract screening. From the remaining 297, thirty-three were excluded. Additionally, 8 articles could not be retrieved, which resulted in the inclusion of 256 articles. The results were grouped according to the type of microleakage evaluation method, resulting in four major categories: colorimetric, imaging, nuclear medicine, and microbiological methods.
Currently, several microleakage assessment techniques are being used, with the dye method being the most reported one. Several variations in the experimental protocols exist, which make it difficult to compare the results. The use of dyes and nuclear medicine methods is sensitive and can be used to evaluate microleakage.
通过范围界定和图谱综述确定用于评估冠状动脉结构修复材料微渗漏的体外技术。
本范围界定综述旨在回答以下问题:“目前用于评估冠状动脉修复材料微渗漏的方法有哪些?”
检索了Medline、Embase、Cochrane图书馆和科学网数据库,以确定2020年至2024年期间发表的相关研究。根据评估方法对所得结果进行分组,并进行叙述性综合分析。
文献检索共识别出1014篇文章,通过标题和摘要筛选排除了353篇出版物。在其余的297篇中,又排除了33篇。此外,有8篇文章无法检索到,最终纳入256篇文章。结果根据微渗漏评估方法的类型进行分组,分为四大类:比色法、成像法、核医学法和微生物学法。
目前正在使用多种微渗漏评估技术,其中染色法是报道最多的一种。实验方案存在多种变体,这使得结果难以比较。染料法和核医学法的使用较为灵敏,可用于评估微渗漏。