用ibrexafungerp治疗人工关节感染
Prosthetic Joint Infection Managed with Ibrexafungerp.
作者信息
Nadarevic Ella, McHugh Jack, Vergidis Paschalis
机构信息
Division of Public Health, Infectious Diseases, and Occupational Medicine, Mayo Clinic, Rochester, MN 55905, USA.
出版信息
J Fungi (Basel). 2025 Jun 11;11(6):442. doi: 10.3390/jof11060442.
Abstract
We report a case of a triazole and echinocandin-resistant right shoulder prosthetic joint infection in a 60-year-old woman. The patient underwent surgery and received the novel triterpenoid antifungal agent ibrexafungerp. She initially improved, but relapsed four months post-treatment. This case highlights the potential role of ibrexafungerp in multidrug-resistant infections.
摘要
我们报告了一例60岁女性右肩关节人工关节感染，该感染对三唑类和棘白菌素耐药。患者接受了手术，并接受了新型三萜类抗真菌药物ibrexafungerp治疗。她最初病情有所改善，但在治疗后四个月复发。该病例突出了ibrexafungerp在多重耐药感染中的潜在作用。
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