University of Alabama at Birmingham, Birmingham VA Medical Center, 1900 University Boulevard, THT 229, Birmingham, AL 35294, USA.
University of Alabama at Birmingham, 1900 University Boulevard, THT 229, Birmingham, AL 35294, USA.
Infect Dis Clin North Am. 2021 Jun;35(2):389-413. doi: 10.1016/j.idc.2021.03.007.
Invasive candidiasis (IC) is a collective term that refers to a group of infectious syndromes caused by a variety of species of Candida, 6 of which cause most cases globally. Candidemia is probably the most commonly recognized syndrome associated with IC; however, Candida can cause invasive infection of any organ, especially visceral organs, vasculature, bones and joints, the eyes and central nervous system. Targeted prevention and empirical therapy are important interventions for patients at high risk for IC, and the current approach should be based on a combination of clinical risk factors and non-culture-based diagnostics, when available.
侵袭性念珠菌病（IC）是一个总称，指的是由多种念珠菌引起的一组感染综合征，其中 6 种在全球范围内导致大多数病例。念珠菌血症可能是与 IC 最相关的综合征；然而，念珠菌可引起任何器官的侵袭性感染，特别是内脏器官、脉管系统、骨骼和关节、眼睛和中枢神经系统。对于有发生 IC 风险的患者，目标性预防和经验性治疗是重要的干预措施，当前的方法应基于临床危险因素和非培养为基础的诊断相结合，在有条件的情况下。
