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评估剪切波弹性成像作为儿童体外冲击波碎石术治疗效果预测指标的价值。

Evaluating shear wave elastography as a predictor of extracorporeal shock wave lithotripsy outcomes in children.

作者信息

Demir Mehmet, Yağmur İsmail, Dere Osman, Albayrak İbrahim Halil, Şengel Abdulhakim

机构信息

Department of Urology, Harran University Faculty of Medicine, Sanliurfa, Turkey.

Department of Pediatric Urology, Harran University Faculty of Medicine, Sanliurfa, Turkey.

出版信息

Urolithiasis. 2025 Jun 25;53(1):126. doi: 10.1007/s00240-025-01796-z.

Abstract

The aim of this study was to demonstrate the utility of Shear Wave Elastography (SWE) in predicting the success of extracorporeal shock wave lithotripsy (ESWL) in pediatric patients. A total of 102 patients < 18 years of age with a diagnosis of kidney stones underwent ESWL between May 2021 and December 2023. SWE measurements of the stones were performed in all patients prior to ESWL. The subjects were divided into two groups: those who responded to ESWL and those who did not. Age, gender, stone location, stone size, body mass index (BMI), Hounsfield Unit (HU), and stone SWE values were compared between the groups. Among the 102 patients included in the study, 78 exhibited a positive response to ESWL. In the responder group, the SWE, HU, and stone size values were significantly lower than the non-responder group (p < 0.05). SWE exhibited significant efficacy in discriminating between responders and non-responders [area under the curve (AUC): 0.979 & p = 0.000]. A SWE cutoff value of 13.70 kPa was identified for patient differentiation [AUC:0.929 & p = 0.000]. SWE appears to be an effective method for predicting the success of ESWL in pediatric patients and may serve as an alternative parameter to HU for pre-treatment evaluation.

摘要

本研究的目的是证明剪切波弹性成像(SWE)在预测儿科患者体外冲击波碎石术(ESWL)成功率方面的效用。2021年5月至2023年12月期间,共有102名年龄小于18岁且诊断为肾结石的患者接受了ESWL治疗。所有患者在ESWL治疗前均进行了结石的SWE测量。受试者分为两组:对ESWL有反应的患者和无反应的患者。比较了两组患者的年龄、性别、结石位置、结石大小、体重指数(BMI)、亨氏单位(HU)和结石SWE值。在纳入研究的102名患者中,78名对ESWL有阳性反应。在有反应组中,SWE、HU和结石大小值显著低于无反应组(p<0.05)。SWE在区分有反应者和无反应者方面显示出显著疗效[曲线下面积(AUC):0.979,p=0.000]。确定SWE截止值为13.70 kPa用于患者区分[AUC:0.929,p=0.000]。SWE似乎是预测儿科患者ESWL成功率的有效方法,并且可以作为HU的替代参数用于治疗前评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c328/12198258/bccd6c9efe48/240_2025_1796_Fig1_HTML.jpg

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