Siewert Nathan, Frenkel Max, Guenther Timothy, Osaki Satoru
University of Wisconsin School of Medicine and Public Health, 600 Highland Ave, Madison, WI, USA.
Medical Scientist Training Program, University of Wisconsin, 600 Highland Ave, Madison, WI, USA.
Int J Surg Case Rep. 2025 Jun 23;133:111550. doi: 10.1016/j.ijscr.2025.111550.
Cardiac myxomas are rare, benign intracardiac tumors that arise from pluripotent mesenchymal stem cells. The vast majority of myxomas consist of mesenchymal stem cells suspended within a mucoid, gelatinous material.
A 55-year-old woman presented with progressive chest pain due to a left atrial myxoma with unusual calcification. A complete resection was performed and pathology confirmed the diagnosis of myxoma with metaplastic ossification.
This case represents the diagnostic challenges of atypical myxomas and emphasizes the importance of multimodal anatomic and functional imaging for accurate preoperative assessment.
This case showcases the heterogeneity of cardiac myxomas, the typical natural history, and the value of multimodal imaging in managing these rare intracardiac tumors.
心脏黏液瘤是罕见的良性心脏肿瘤,起源于多能间充质干细胞。绝大多数黏液瘤由悬浮在黏液样、胶冻状物质中的间充质干细胞组成。
一名55岁女性因左心房黏液瘤伴异常钙化出现进行性胸痛。进行了完整切除,病理证实为伴有化生骨化的黏液瘤诊断。
该病例代表了非典型黏液瘤的诊断挑战,并强调了多模态解剖和功能成像对于准确术前评估的重要性。
该病例展示了心脏黏液瘤的异质性、典型自然病程以及多模态成像在处理这些罕见心脏肿瘤中的价值。