心脏黏液瘤的临床病理分析：61 例患者 7 年的经验。
Clinicopathologic analysis of cardiac myxomas: Seven years' experience with 61 patients.
出版信息
J Thorac Dis. 2012 Jun 1;4(3):272-83. doi: 10.3978/j.issn.2072-1439.2012.05.07.
OBJECTIVE
Cardiac myxomas are the most common primary neoplasms of heart. The present study was performed on the 61 cases of patients with cardiac myxoma, in order to investigate the tumors' clinical and pathological features, and to identify the relationship between the pathological characteristics and clinical behaviors.
METHODS
A total of 61 cardiac myxoma cases were analyzed and reviewed retrospectively, including the clinical presentations, physical examinations, and echocardiography, electrocardiography, and pathology documents.
RESULTS
The total patient cohort was made up of 37 women and 24 men. The average age at diagnosis was 48.8 years in males and 51.9 years in females. The most common complaint was dyspnea (37 cases, 60.7%) and the most common sign was systolic murmur (30 cases, 49.2%). Two surface structures and three tumor cell arrangement patterns were observed, and statistical analysis revealed the surface structure was related to the cell arrangement pattern. However, neither the cell arrangement pattern nor the tumor surface structure showed a significant correlation with the clinical presentation.
CONCLUSIONS
The present study showed the pathological profiles of cardiac myxomas were not related to the clinical presentations. The results of our study indicate morphologic classifications of cardiac myxomas may not be significant for clinical practice.
目的
心脏黏液瘤是心脏最常见的原发性肿瘤。本研究对 61 例心脏黏液瘤患者进行了研究，旨在探讨肿瘤的临床和病理特征，并确定病理特征与临床行为之间的关系。
方法
回顾性分析了 61 例心脏黏液瘤病例，包括临床表现、体格检查以及超声心动图、心电图和病理文件。
结果
总患者队列由 37 名女性和 24 名男性组成。男性诊断时的平均年龄为 48.8 岁，女性为 51.9 岁。最常见的主诉是呼吸困难（37 例，60.7%），最常见的体征是收缩期杂音（30 例，49.2%）。观察到两种表面结构和三种肿瘤细胞排列模式，统计分析显示表面结构与细胞排列模式有关。然而，细胞排列模式和肿瘤表面结构均与临床表现无显著相关性。
结论
本研究表明心脏黏液瘤的病理特征与临床表现无关。我们的研究结果表明，心脏黏液瘤的形态学分类对于临床实践可能意义不大。
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