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2024年美国新型隐球菌抗原血症筛查的新发感染网络调查

Emerging Infections Network Survey of Screening for Cryptococcal Antigenemia, United States, 2024.

作者信息

Benedict Kaitlin, Jordan Alexander, Gold Jeremy A W, Smith Dallas J, Chiller Tom, Hennessee Ian, Polgreen Philip M, Beekmann Susan E

出版信息

Emerg Infect Dis. 2025 Jul;31(7):1493-1495. doi: 10.3201/eid3107.250295.

DOI:10.3201/eid3107.250295
PMID:40562736
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12205458/
Abstract

We polled infectious disease specialists about cryptococcal antigen screening for patients initiating HIV antiretroviral therapy. Of 215 respondents, 33% reported typically obtaining screening for patients with CD4 counts <200 cells/mm and 63% for counts <100 CD4 cells/mm. Uncertainty about cryptococcal antigen screening benefits and recommendations suggests opportunities for education and increased screening.

摘要

我们就开始接受人类免疫缺陷病毒(HIV)抗逆转录病毒治疗的患者进行隐球菌抗原筛查一事,对传染病专家进行了调查。在215名受访者中,33%报告称通常会对CD4细胞计数低于200个/立方毫米的患者进行筛查,63%的受访者会对CD4细胞计数低于100个/立方毫米的患者进行筛查。对于隐球菌抗原筛查的益处和建议存在不确定性,这表明有开展教育和增加筛查的机会。

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本文引用的文献

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Epidemiology of Cryptococcosis Among Patients With Commercial Health Insurance and Patients With Medicaid, United States, 2016-2022.2016 - 2022年美国商业健康保险患者和医疗补助患者中隐球菌病的流行病学
Open Forum Infect Dis. 2024 May 6;11(5):ofae260. doi: 10.1093/ofid/ofae260. eCollection 2024 May.
2
The Role of Frequent Screening or Diagnostic Testing of Serum Cryptococcal Antigen in Liver Transplant Recipients: A Descriptive Epidemiology.血清隐球菌抗原的频繁筛查或诊断检测在肝移植受者中的作用:描述性流行病学
Open Forum Infect Dis. 2024 May 17;11(5):ofae255. doi: 10.1093/ofid/ofae255. eCollection 2024 May.
3
Global guideline for the diagnosis and management of cryptococcosis: an initiative of the ECMM and ISHAM in cooperation with the ASM.全球隐球菌病诊断和管理指南:欧洲癌症研究与治疗组织和国际系统性真菌感染学会与美国微生物学会合作开展的一项倡议。
Lancet Infect Dis. 2024 Aug;24(8):e495-e512. doi: 10.1016/S1473-3099(23)00731-4. Epub 2024 Feb 9.
4
Demographic and Socioeconomic Factors Associated with Fungal Infection Risk, United States, 2019.与真菌感染风险相关的人口统计学和社会经济学因素,美国,2019 年。
Emerg Infect Dis. 2022 Oct;28(10):1955-69. doi: 10.3201/eid2810.220391.
5
Impact of Routine Cryptococcal Antigen Screening and Targeted Preemptive Fluconazole Therapy in Antiretroviral-naive Human Immunodeficiency Virus-infected Adults With CD4 Cell Counts <100/μL: A Systematic Review and Meta-analysis.抗逆转录病毒治疗初治的 CD4 细胞计数<100/μL 的人类免疫缺陷病毒感染成人中,常规隐球菌抗原筛查和目标性抢先氟康唑治疗的影响:系统评价和荟萃分析。
Clin Infect Dis. 2019 Feb 1;68(4):688-698. doi: 10.1093/cid/ciy567.
6
The Infectious Diseases Society of America emerging infections network: bridging the gap between clinical infectious diseases and public health.美国传染病学会新发感染网络:弥合临床传染病与公共卫生之间的差距。
Clin Infect Dis. 2014 Apr;58(7):991-6. doi: 10.1093/cid/cit932. Epub 2014 Jan 7.