Tang Ze, Wang Ziwei, Wang Xinbao
Department of Pediatrics, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.
Children (Basel). 2025 Jun 9;12(6):747. doi: 10.3390/children12060747.
Sudden Infant Death Syndrome (SIDS) remains an important global health concern despite its decline in recent decades. This research assesses the global, regional, and national tendencies in SIDS mortality and DALYs from 1991 to 2021, highlighting the differences across various sociodemographic indexes (SDIs). : Utilizing data from the Global Burden of Disease (GBD) study 2021, SIDS mortality and DALYs were evaluated across different global regions, SDI categories, and age groups. The trends over the study period were determined by conducting estimated annual percentage change (EAPC) analyses. : Between 1991 and 2021, the global SIDS mortality rate reduced greatly from 74,782 deaths (58.72 per 100,000 infants) to 30,608 deaths (24.16 per 100,000 infants), showing an EAPC of -3.01%. Similarly, the global DALYs decreased from 6,710,608 to 2,746,174. The biggest decline (EAPC: -5.25%) occurred in the high-SDI regions, whereas the low-SDI regions displayed a minimal decline (EAPC: -2.74%). Infants who were 1-5 months old uniformly had the highest mortality and DALY rates. Gender differences persisted, with larger rates discovered among males. The regional differences remained prominent, with the low-SDI states experiencing a much higher burden. : Although there have been remarkable global advancements, great differences in the SIDS burden persist, mainly boosted by socioeconomic unfairness and healthcare access. Improved targeted interventions mitigating these modifiable risks and enhancing healthcare infrastructure in low-SDI regions are the keys to further reducing the global SIDS burden.
尽管近几十年来婴儿猝死综合征（SIDS）的发生率有所下降，但它仍然是一个重要的全球健康问题。本研究评估了1991年至2021年期间SIDS死亡率和伤残调整生命年（DALYs）的全球、区域和国家趋势，突出了不同社会人口学指数（SDIs）之间的差异。：利用2021年全球疾病负担（GBD）研究的数据，对不同全球区域、SDI类别和年龄组的SIDS死亡率和DALYs进行了评估。通过进行估计年度百分比变化（EAPC）分析来确定研究期间的趋势。：1991年至2021年期间，全球SIDS死亡率大幅下降，从74782例死亡（每10万名婴儿中有58.72例）降至30608例死亡（每10万名婴儿中有24.16例），EAPC为-3.01%。同样，全球DALYs从6710608降至2746174。高SDI地区下降幅度最大（EAPC：-5.25%），而低SDI地区下降幅度最小（EAPC：-2.74%）。1至5个月大的婴儿死亡率和DALY率始终最高。性别差异依然存在，男性的发生率更高。区域差异仍然很突出，低SDI国家的负担要高得多。：尽管全球取得了显著进展，但SIDS负担的巨大差异仍然存在，主要是由社会经济不公平和医疗保健可及性推动的。改善针对性干预措施以减轻这些可改变的风险，并加强低SDI地区的医疗基础设施，是进一步降低全球SIDS负担的关键。
