Trninić Dijana, Jovanic Jelena, Lazarevic Aleksandar, Marjanovic Miron, Kovacevic Sinisa, Dobrijevic Neno, Pejicic Popovic Snjezana
Department of Cardiology, University Clinical Center of the Republic of Srpska, 78000 Banja Luka, Bosnia and Herzegovina.
Faculty of Medicine, University of Banja Luka, 78000 Banja Luka, Bosnia and Herzegovina.
Diagnostics (Basel). 2025 Jun 10;15(12):1473. doi: 10.3390/diagnostics15121473.
: Dobutamine stress echocardiography (DSE) is a non-invasive diagnostic technique commonly employed in routine clinical practice to identify coronary artery disease. Emerging echocardiographic methods, including strain and strain rate imaging, quantify alterations in myocardial contractility and may improve the diagnostic accuracy of DSE. The main aim of this study was to assess the correlation between visual interpretation and longitudinal strain during dobutamine stress echocardiography. : Our study was observational and was conducted at the Cardiology Clinic of the University Clinical Center of the Republic of Srpska. It included 70 patients who underwent dobutamine stress echocardiography. The patients were divided into two groups (diagnostic and viable study). A visual assessment of segmental contractility of the left ventricle was performed, as well as an assessment of contractility with longitudinal strain (LS) during the test. : The median baseline LS of segments without impaired contractility in the diagnostic study was -20% (-21 to -18) and, at the peak of the test, -22% (-23 to -21), which was statistically significant ( < 0.05). The median baseline LS in the segments with impaired contractility was -17% (-18 to -16) and, at the peak of the test, -13% (-15 to -12), which was statistically significant ( < 0.05). In the viability study, the average baseline LS in the segments with improved contractility was -8% (-11 to -7) and, at the peak of the test, -14% (-17 to -13), which was statistically significant ( < 0.05). The average baseline LS in the segments without improved contractility was -6% (-5 to -7) and, at the peak of the test, -2% (-3 to -0), which was statistically significant ( < 0.05). : Our study indicates a good correlation between a visual assessment of left ventricular segment contractility and longitudinal strain during dobutamine stress echocardiography.
多巴酚丁胺负荷超声心动图（DSE）是一种在常规临床实践中常用的非侵入性诊断技术，用于识别冠状动脉疾病。新兴的超声心动图方法，包括应变和应变率成像，可量化心肌收缩力的变化，并可能提高DSE的诊断准确性。本研究的主要目的是评估多巴酚丁胺负荷超声心动图期间视觉解读与纵向应变之间的相关性。
我们的研究是观察性的，在塞尔维亚共和国大学临床中心心脏病科进行。研究纳入了70例行多巴酚丁胺负荷超声心动图检查的患者。患者被分为两组（诊断组和存活组）。对左心室节段性收缩力进行了视觉评估，并在检查期间用纵向应变（LS）评估了收缩力。
诊断组中收缩力未受损节段的基线LS中位数为-20%（-21至-18），在检查峰值时为-22%（-23至-21），具有统计学意义（<0.05）。收缩力受损节段的基线LS中位数为-17%（-18至-16），在检查峰值时为-13%（-15至-12），具有统计学意义（<0.05）。在存活组中，收缩力改善节段的平均基线LS为-8%（-11至-7），在检查峰值时为-14%（-17至-13），具有统计学意义（<0.05）。收缩力未改善节段的平均基线LS为-6%（-5至-7），在检查峰值时为-2%（-3至-0），具有统计学意义（<0.05）。
我们的研究表明，多巴酚丁胺负荷超声心动图期间左心室节段收缩力的视觉评估与纵向应变之间具有良好的相关性。
