Nguyen Kathy, Rao Tanushree
School of Clinical Medicine, Faculty of Medicine and Health, University of New South Wales, Sydney, NSW 2033, Australia.
Minimally Invasive Gynecologic Surgery Unit, Liverpool Hospital, Liverpool, NSW 2170, Australia.
Healthcare (Basel). 2025 Jun 6;13(12):1367. doi: 10.3390/healthcare13121367.
Cotyledonoid dissecting leiomyoma (CDL), also known as Sternberg tumour, is a rare variant of leiomyoma that can be easily mistaken for a malignant neoplasm on clinical and radiological examination, posing a diagnostic challenge for clinicians. Although the tumour can extend to neighbouring organs, it typically does not invade them and is considered benign. Therefore, it is essential to recognise and differentiate this leiomyoma variant from other malignancies to avoid misdiagnosis and overtreatment. This report depicts a unique case of CDL misdiagnosed as an ovarian tumour in a woman in her late 50s with post-menopausal bleeding and pelvic pressure. We initially planned and proceeded with a diagnostic laparoscopy and laparoscopic oophorectomy of the right ovarian mass, during which an intraoperative surprise of a retroperitoneal mass was explored and subsequently biopsied. The final histopathology confirmed the presence of the rare fibroid variant CDL. The accompanying surgical video is among the first to feature a laparoscopic surgery of CDL and details the intraoperative findings and laparoscopic resection techniques utilised in this case. Given its rarity and non-specific clinical and radiological findings, diagnosing CDL pre-operatively can be challenging. This case prompts recognition and awareness of CDL and highlights the importance of careful consideration of uncommon differential diagnoses and thorough intraoperative exploration, with the goal of preventing the misdiagnosis and, consequently, overtreatment of unknown masses.
子叶样解剖性平滑肌瘤(CDL),也称为施特恩贝格瘤,是平滑肌瘤的一种罕见变体,在临床和放射学检查中很容易被误诊为恶性肿瘤,给临床医生带来诊断挑战。尽管肿瘤可延伸至邻近器官,但通常不会侵犯它们,被认为是良性的。因此,识别并将这种平滑肌瘤变体与其他恶性肿瘤区分开来,以避免误诊和过度治疗至关重要。本报告描述了一例独特的CDL病例,该病例发生在一名50多岁绝经后出血并伴有盆腔压迫感的女性身上,最初被误诊为卵巢肿瘤。我们最初计划并进行了诊断性腹腔镜检查及对右侧卵巢肿块的腹腔镜卵巢切除术,在此过程中发现了一个腹膜后肿块并进行了活检。最终的组织病理学检查证实存在罕见的纤维瘤变体CDL。随附的手术视频是最早展示CDL腹腔镜手术的视频之一,详细介绍了该病例的术中发现及所采用的腹腔镜切除技术。鉴于其罕见性以及非特异性的临床和放射学表现,术前诊断CDL具有挑战性。该病例促使人们认识和了解CDL,并强调了仔细考虑罕见鉴别诊断及进行全面术中探查的重要性,目的是防止对不明肿块的误诊以及由此导致的过度治疗。