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Endurant人工血管内支架在肾下型腹主动脉瘤合并肾下颈部解剖结构宽阔或呈圆锥形时的性能表现

The Performance of the Endurant Endoprosthesis in an Infrarenal Aortic Aneurysm with a Wide or Conical-Shaped Infrarenal Neck Anatomy.

作者信息

Plug Maaike, Holewijn Suzanne, Meershoek Armelle, van der Veen Daphne, Reijnen Michel M P J

机构信息

Department of Surgery, Rijnstate Hospital, Wagnerlaan 55, 6815 AD Arnhem, The Netherlands.

Multi-Modality Medical Imaging Group, TechMed Centre, University of Twente, 7522 NB Enschede, The Netherlands.

出版信息

J Clin Med. 2025 Jun 11;14(12):4133. doi: 10.3390/jcm14124133.

Abstract

Wide and conical-shaped infrarenal necks are risk factors for neck-related complications after Endovascular Aorta Aneurysm Repair (EVAR). The aim of this study is to investigate the performance of the Endurant endoprosthesis in wide/conical-shaped aortic neck anatomies compared to its performance in a normal infrarenal neck (reference group). : A single-center, retrospective observational cohort study was performed, including consecutive subjects with an infrarenal abdominal aortic aneurysm, treated electively with an Endurant endoprosthesis. The primary endpoint was the freedom from aneurysm-related reinterventions through 1 year. Secondary endpoints included proximal fixation failure, type IA endoleak, stent migration, aneurysm sac remodeling, aneurysm-related mortality, freedom from reinterventions throughout available follow-up, and rupture. : A total of 268 patients were included, with a mean age of 73.3 years, and 85.1% were male. Freedom from aneurysm-related reinterventions was significantly lower in the wide-neck group (60.0%) compared to the reference group (81.1%; = 0.018) but not for the conical-neck group (70.3%; = 0.286). Median time to first reintervention was 1.7 (IQR 0.8; 4.4 years) in the reference group, 2.9 years (IQR 0.3; 5.0 years) in the wide-neck group ( = 0.547) and 3.8 years (IQR 0.4; 6.5) in the conical-neck group ( = 0.123). The proximal fixation failure rate was 7.4% in the wide-neck group compared to 3.3% in the reference group ( = 0.155) and 1.7% in the conical-neck group ( = 0.525). The type IA endoleak rate was 4.9% in the wide-neck group versus 3.3% in the reference group ( = 0.250). : In the group with wide necks, reintervention-free survival was lower compared to the reference group, which seems to be driven by proximal fixation failure.

摘要

肾下型颈部宽阔且呈圆锥形是血管腔内腹主动脉瘤修复术(EVAR)后发生颈部相关并发症的危险因素。本研究的目的是比较Endurant人工血管在宽阔/圆锥形主动脉颈部解剖结构中的性能与其在正常肾下型颈部(参照组)中的性能。:进行了一项单中心回顾性观察队列研究,纳入连续接受Endurant人工血管择期治疗的肾下腹主动脉瘤患者。主要终点是1年内无动脉瘤相关再干预。次要终点包括近端固定失败、IA型内漏、支架移位、动脉瘤囊重塑、动脉瘤相关死亡率、在整个可用随访期内无再干预以及动脉瘤破裂。:共纳入268例患者,平均年龄73.3岁,85.1%为男性。与参照组(81.1%;P = 0.018)相比,宽阔颈部组无动脉瘤相关再干预的比例显著较低(60.0%),但圆锥形颈部组(70.3%;P = 0.286)并非如此。参照组首次再干预的中位时间为1.7年(四分位间距0.8;4.4年),宽阔颈部组为2.9年(四分位间距0.3;5.0年)(P = 0.547),圆锥形颈部组为3.8年(四分位间距0.4;6.5年)(P = 0.123)。宽阔颈部组近端固定失败率为7.4%,参照组为3.3%(P = 0.155),圆锥形颈部组为1.7%(P = 0.525)。宽阔颈部组IA型内漏率为4.9%,参照组为3.3%(P = 0.250)。:在宽阔颈部组中,无再干预生存率低于参照组,这似乎是由近端固定失败导致的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/869b/12194267/8b377f938f23/jcm-14-04133-g001.jpg

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