Plug Maaike, Holewijn Suzanne, Meershoek Armelle, van der Veen Daphne, Reijnen Michel M P J
Department of Surgery, Rijnstate Hospital, Wagnerlaan 55, 6815 AD Arnhem, The Netherlands.
Multi-Modality Medical Imaging Group, TechMed Centre, University of Twente, 7522 NB Enschede, The Netherlands.
J Clin Med. 2025 Jun 11;14(12):4133. doi: 10.3390/jcm14124133.
Wide and conical-shaped infrarenal necks are risk factors for neck-related complications after Endovascular Aorta Aneurysm Repair (EVAR). The aim of this study is to investigate the performance of the Endurant endoprosthesis in wide/conical-shaped aortic neck anatomies compared to its performance in a normal infrarenal neck (reference group). : A single-center, retrospective observational cohort study was performed, including consecutive subjects with an infrarenal abdominal aortic aneurysm, treated electively with an Endurant endoprosthesis. The primary endpoint was the freedom from aneurysm-related reinterventions through 1 year. Secondary endpoints included proximal fixation failure, type IA endoleak, stent migration, aneurysm sac remodeling, aneurysm-related mortality, freedom from reinterventions throughout available follow-up, and rupture. : A total of 268 patients were included, with a mean age of 73.3 years, and 85.1% were male. Freedom from aneurysm-related reinterventions was significantly lower in the wide-neck group (60.0%) compared to the reference group (81.1%; = 0.018) but not for the conical-neck group (70.3%; = 0.286). Median time to first reintervention was 1.7 (IQR 0.8; 4.4 years) in the reference group, 2.9 years (IQR 0.3; 5.0 years) in the wide-neck group ( = 0.547) and 3.8 years (IQR 0.4; 6.5) in the conical-neck group ( = 0.123). The proximal fixation failure rate was 7.4% in the wide-neck group compared to 3.3% in the reference group ( = 0.155) and 1.7% in the conical-neck group ( = 0.525). The type IA endoleak rate was 4.9% in the wide-neck group versus 3.3% in the reference group ( = 0.250). : In the group with wide necks, reintervention-free survival was lower compared to the reference group, which seems to be driven by proximal fixation failure.
肾下型颈部宽阔且呈圆锥形是血管腔内腹主动脉瘤修复术(EVAR)后发生颈部相关并发症的危险因素。本研究的目的是比较Endurant人工血管在宽阔/圆锥形主动脉颈部解剖结构中的性能与其在正常肾下型颈部(参照组)中的性能。:进行了一项单中心回顾性观察队列研究,纳入连续接受Endurant人工血管择期治疗的肾下腹主动脉瘤患者。主要终点是1年内无动脉瘤相关再干预。次要终点包括近端固定失败、IA型内漏、支架移位、动脉瘤囊重塑、动脉瘤相关死亡率、在整个可用随访期内无再干预以及动脉瘤破裂。:共纳入268例患者,平均年龄73.3岁,85.1%为男性。与参照组(81.1%;P = 0.018)相比,宽阔颈部组无动脉瘤相关再干预的比例显著较低(60.0%),但圆锥形颈部组(70.3%;P = 0.286)并非如此。参照组首次再干预的中位时间为1.7年(四分位间距0.8;4.4年),宽阔颈部组为2.9年(四分位间距0.3;5.0年)(P = 0.547),圆锥形颈部组为3.8年(四分位间距0.4;6.5年)(P = 0.123)。宽阔颈部组近端固定失败率为7.4%,参照组为3.3%(P = 0.155),圆锥形颈部组为1.7%(P = 0.525)。宽阔颈部组IA型内漏率为4.9%,参照组为3.3%(P = 0.250)。:在宽阔颈部组中,无再干预生存率低于参照组,这似乎是由近端固定失败导致的。