Policicchio Domenico, Boniferro Benedetta, Lo Turco Erica, Mauro Giuseppe, Veraldi Antonio, Vescio Virginia, Vescio Giuseppe, Dipellegrini Giosuè
Department of Neurosurgery, Azienda Ospedaliero Universitaria "Renato Dulbecco" di Catanzaro, 88100 Catanzaro, Italy.
Department of Radiology, Azienda Ospedaliero Universitaria "Renato Dulbecco" di Catanzaro, 88100 Catanzaro, Italy.
J Clin Med. 2025 Jun 14;14(12):4235. doi: 10.3390/jcm14124235.
Although percutaneous laser disc decompression (PLDD) has been proposed as an alternative to conventional surgery for lumbar disc herniation (LDH), we specifically propose it for patients with contained herniations where standard surgical intervention is not the first option. This study evaluates PLDD compared to conservative therapy as an early treatment alternative. : This retrospective observational study compared PLDD to conservative treatment in adult patients with contained LDH. All patients underwent 3 months of standard conservative therapy. Those who remained dissatisfied according to the Visual Analog Scale (VAS) and/or Macnab criteria were then treated with PLDD. We analyzed outcomes from both treatment phases using the Wilcoxon signed-rank test and the Mann-Whitney U test. : 121 patients underwent outpatient evaluation for LDH and received an average of 90 days of conservative therapy. Of these 103 patients, dissatisfied with the outcomes of conservative treatment, subsequently underwent PLDD. Following conservative treatment, the average VAS score reduction was 4.1%. Six months after PLDD, the VAS scores demonstrated a significant reduction, with an average decrease of 30% ( < 0.0001). In terms of functional outcomes assessed by the Macnab criteria, 39.8% of patients treated with PLDD achieved 'Excellent' or 'Good' outcomes, compared to only 11.4% after conservative treatment. : PLDD appears to be a viable alternative to conservative therapy for this subgroup of patients with contained LDH. It may be beneficial to propose PLDD early in the therapeutic regimen to accelerate short term clinical improvement. Further studies are required to evaluate the long term efficacy of this treatment approach.
尽管经皮激光椎间盘减压术(PLDD)已被提议作为腰椎间盘突出症(LDH)传统手术的替代方法,但我们特别建议将其用于局限性椎间盘突出的患者,这类患者并不首选标准手术干预。本研究评估了PLDD与保守治疗相比作为早期治疗选择的效果。:这项回顾性观察研究比较了PLDD与成年局限性LDH患者保守治疗的效果。所有患者均接受了3个月的标准保守治疗。根据视觉模拟量表(VAS)和/或Macnab标准仍不满意的患者随后接受PLDD治疗。我们使用Wilcoxon符号秩检验和Mann-Whitney U检验分析了两个治疗阶段的结果。:121例患者因LDH接受门诊评估,平均接受了90天的保守治疗。其中103例患者对保守治疗结果不满意,随后接受了PLDD治疗。保守治疗后,VAS评分平均降低了4.1%。PLDD治疗6个月后,VAS评分显著降低,平均降低了30%(<0.0001)。根据Macnab标准评估的功能结果,接受PLDD治疗的患者中有39.8%达到了“优”或“良”的结果,而保守治疗后只有11.4%。:对于这一局限性LDH患者亚组,PLDD似乎是保守治疗的可行替代方法。在治疗方案中尽早提出PLDD可能有助于加速短期临床改善。需要进一步研究来评估这种治疗方法的长期疗效。