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胎盘植入谱系疾病的母体及临床结局:来自巴林一项回顾性研究的见解

Maternal and Clinical Outcomes of Placenta Accreta Spectrum: Insights from a Retrospective Study in Bahrain.

作者信息

Selby Chacko Kareeza, AlSubeaei Reem Satam, Sunil Nair Soumya, Khalil Kazi Nusrat, Jeddy Rafiea

机构信息

School of Medicine, Royal College of Surgeons in Ireland-Bahrain (RCSI-Bahrain), Busaiteen P.O. Box 15503, Bahrain.

Department of Obstetrics and Gynecology, Salmaniya Medical Complex, Manama P.O. Box 12, Bahrain.

出版信息

Life (Basel). 2025 Jun 18;15(6):978. doi: 10.3390/life15060978.

DOI:10.3390/life15060978
PMID:40566629
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12194568/
Abstract

Placenta accreta spectrum (PAS) refers to a group of abnormal placental attachments in which the placenta adheres too deeply to the uterine wall, with varying degrees of invasion classified as accreta, increta, or percreta. Increased rates of uterine surgeries, advanced maternal age, and cesarean deliveries have all contributed to an increase in the incidence of PAS. Complications associated with PAS can lead to severe intrapartum or postpartum hemorrhage, hysterectomy, and significant maternal morbidity, making early diagnosis and management crucial for improving outcomes. Understanding the epidemiology and risk factors of PAS is crucial for developing early detection protocols and preventive strategies. Localized data, particularly from Bahrain, can inform targeted care approaches and optimize resource allocation, ultimately leading to improved clinical guidelines, enhanced patient education, and better healthcare outcomes for affected women. There are growing concerns about the impact of PAS on maternal health and healthcare resources in Bahrain, similar to trends observed in other regions. To improve patient education and management strategies, it is essential to comprehend the regional patterns, characteristics, and outcomes associated with PAS. However, the absence of comprehensive data specific to Bahrain hinders effective clinical decision-making and policy development. Addressing this gap is imperative for advancing maternal healthcare in the region.

摘要

胎盘植入谱系障碍(PAS)指的是一组胎盘异常附着情况,即胎盘与子宫壁粘连过深,根据侵入程度不同分为粘连性胎盘、植入性胎盘或穿透性胎盘。子宫手术率上升、产妇年龄增大以及剖宫产率上升均导致了PAS发病率的增加。与PAS相关的并发症可导致严重的分娩期或产后出血、子宫切除术以及产妇出现严重发病情况,因此早期诊断和处理对于改善结局至关重要。了解PAS的流行病学和危险因素对于制定早期检测方案和预防策略至关重要。本地数据,尤其是来自巴林的数据,可为针对性的护理方法提供依据并优化资源分配,最终促成改进临床指南、加强患者教育以及为受影响妇女带来更好的医疗保健结局。与其他地区观察到的趋势类似,人们越来越担心PAS对巴林产妇健康和医疗资源的影响。为了改进患者教育和管理策略,必须了解与PAS相关的区域模式、特征和结局。然而,缺乏巴林的具体综合数据阻碍了有效的临床决策和政策制定。弥补这一差距对于推进该地区的产妇医疗保健至关重要。

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本文引用的文献

1
Conservative management of placenta accreta spectrum is associated with improved surgical outcomes compared to cesarean hysterectomy: a systematic review and meta-analysis.与剖宫产子宫切除术相比,胎盘植入谱系疾病的保守治疗与更好的手术结局相关:一项系统评价和荟萃分析。
Am J Obstet Gynecol. 2025 May;232(5):432-452.e3. doi: 10.1016/j.ajog.2025.01.030. Epub 2025 Jan 28.
2
Exploring pathophysiological insights to improve diagnostic utility of ultrasound markers for distinguishing placenta accreta spectrum from uterine-scar dehiscence.探索病理生理学见解以提高超声标志物在鉴别胎盘植入谱系疾病与子宫瘢痕裂开方面的诊断效用。
Ultrasound Obstet Gynecol. 2025 Jan;65(1):85-93. doi: 10.1002/uog.29144. Epub 2024 Dec 15.
3
Intended Conservative Management Versus Caesarean Hysterectomy for Known or Suspected Placenta Accreta Spectrum: A Cost-Effectiveness Analysis.已知或疑似胎盘植入谱系疾病的预期保守治疗与剖宫产子宫切除术:成本效益分析
BJOG. 2025 Jul;132(8):1096-1103. doi: 10.1111/1471-0528.18025. Epub 2024 Dec 5.
4
Bladder involvement in placenta accreta spectrum disorders: 2D US combined with the 3D crystal Vue and MRI comparative analysis.胎盘植入谱系疾病中的膀胱受累:2D US 联合 3D 水晶 Vue 和 MRI 的对比分析。
BMC Pregnancy Childbirth. 2024 Nov 26;24(1):788. doi: 10.1186/s12884-024-06997-9.
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Maternal outcomes of conservative management and cesarean hysterectomy for placenta accreta spectrum disorders: a systematic review and meta-analysis.保守治疗与剖宫产子宫切除术治疗胎盘植入谱系疾病的产妇结局:系统评价和荟萃分析。
BMC Pregnancy Childbirth. 2024 Jul 5;24(1):463. doi: 10.1186/s12884-024-06658-x.
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Incidence, risk factors and maternal outcomes of unsuspected placenta accreta spectrum disorders: a retrospective cohort study.不明原因胎盘植入谱系疾病的发生率、危险因素和母婴结局:一项回顾性队列研究。
BMC Pregnancy Childbirth. 2024 Jan 23;24(1):76. doi: 10.1186/s12884-024-06254-z.
7
A Retrospective Study of Maternal and Neonatal Outcome in Placenta Accreta Spectrum After Planned or Emergency Delivery From a Tertiary Care Centre in North India.印度北部一家三级护理中心计划性或急诊分娩后胎盘植入谱系疾病母婴结局的回顾性研究
Cureus. 2023 Sep 5;15(9):e44725. doi: 10.7759/cureus.44725. eCollection 2023 Sep.
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J Matern Fetal Neonatal Med. 2023 Dec;36(2):2232076. doi: 10.1080/14767058.2023.2232076.
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Taiwan J Obstet Gynecol. 2021 May;60(3):395-396. doi: 10.1016/j.tjog.2021.03.001.
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