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韩国一项基于全国人群的研究:髋关节发育不良的发病率趋势及围产期危险因素

Incidence trends and perinatal risk factors of developmental dysplasia of the hip: a nationwide population-based study from South Korea.

作者信息

Bae Kunhyung, Cha Jong Ho, Kim Jiyoung Agatha, Ryu Soorack, Na Jae Yoon, Choi Young-Jin

机构信息

Department of Orthopaedic Surgery, Hanyang University Hospital, Hanyang University College of Medicine, Seoul, Republic of South Korea.

Department of Pediatrics, Hanyang University Hospital, Seoul, Republic of South Korea.

出版信息

Acta Orthop. 2025 Jun 26;96:477-484. doi: 10.2340/17453674.2025.43980.

Abstract

BACKGROUND AND PURPOSE

South Korea has implemented the National Health Screening Program for Infants and Children (NHSPIC), which includes clinical hip screening with selective hip ultrasonography beginning at 4 months of age. We aimed to investigate the trends in developmental dysplasia of the hip (DDH), associated risk factors, and growth and motor developmental outcomes up to preschool age.

METHODS

We included a retrospective, population-based birth cohort of children born between 2008 and 2015. Patients diagnosed with DDH were stratified by age at detection (early diagnosed [<1 year] vs late diagnosed [≥1 year]) and treatment modalities (major surgery, minor surgery, or nonoperative). Growth and motor developmental outcomes were assessed using NHSPIC data collected up to 6 years of age.

RESULTS

Among 2,518,805 children, 4,854 (0.19%) were diagnosed with DDH. The incidence of DDH increased from 1.29 to 2.37 per 1,000 individuals, with the incidence of early diagnosed DDH increased from 0.70 to 1.94 per 1,000. However, the rate of surgical treatment remained unchanged (0.19-0.28 per 1,000). Children who underwent surgical treatment for DDH had a significantly higher incidences of short stature, and delayed gross motor development.

CONCLUSION

After the introduction of the NHSPIC hip screening program, incidences of overall and early diagnosed DDH increased, whereas the surgical treatment rate showed no significant change. Surgical treatment for DDH was significantly associated with both short stature and delayed gross motor development.

摘要

背景与目的

韩国实施了婴幼儿国家健康筛查计划(NHSPIC),其中包括从4个月大开始进行选择性髋关节超声检查的临床髋关节筛查。我们旨在调查髋关节发育不良(DDH)的趋势、相关危险因素以及学龄前儿童的生长和运动发育结果。

方法

我们纳入了一个基于人群的回顾性出生队列,研究对象为2008年至2015年出生的儿童。被诊断为DDH的患者按检测时的年龄(早期诊断[<1岁]与晚期诊断[≥1岁])和治疗方式(大手术、小手术或非手术)进行分层。使用收集的6岁以下儿童的NHSPIC数据评估生长和运动发育结果。

结果

在2,518,805名儿童中,4,854名(0.19%)被诊断为DDH。DDH的发病率从每1000人中的1.29例增加到2.37例,早期诊断的DDH发病率从每1000人中的0.70例增加到1.94例。然而,手术治疗率保持不变(每1000人中0.19 - 0.

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