He Zhanyang, Sun Gang, Zhu Houwei, Ye Binyong, Zheng Zhe, He Xiaolong, Pan Huiju
College of Physical Education and Health Sciences, Zhejiang Normal University, Jinhua, China.
Front Bioeng Biotechnol. 2025 Jun 3;13:1587573. doi: 10.3389/fbioe.2025.1587573. eCollection 2025.
Previous research suggests that although fatigue accumulates during competitions and at season's end, anterior cruciate ligament (ACL) injuries do not significantly increase, with peripheral fatigue-induced muscle weakness potentially playing a key role. The aim of this study is to systematically review the effects of different peripheral fatigue interventions on biomechanical variables associated with ACL injury risk during landing tasks. A systematic search was conducted in five databases Web of Science, Scopus, PubMed, EBSCO, and Cochrane Library up to September 2024. The evidence classification system was used to grade the evidence on lower limb biomechanical changes. A total of 12 studies, involving 217 participants (105 males, 112 females), were included. These studies examined 9 peripheral fatigue protocols, 14 kinematic variables, and 16 kinetic variables. Among the 14 kinematic variables reviewed, strong evidence indicates increased knee internal rotation angles at peak vertical ground reaction force (vGRF) during landing tasks after the knee flexors and extensors peripheral fatigue protocols (Effect size = 0.24-0.68). For the 16 kinetic variables reviewed, strong evidence only suggests a reduction in peak vGRF during landing tasks after knee flexors and extensors peripheral fatigue protocols (Effect size = 0.12-0.32). In conclusion, we found that only two peripheral fatigue interventions were supported by evidence, while most kinematic and kinetic variables showed conflicting results, underscoring the need for further research. Such improvements will help clarify whether current neuromuscular ACL injury prevention programs need to be adapted to account for the biomechanical changes brought about by peripheral fatigue. clinicaltrials.gov, identifier CRD42024593839.
先前的研究表明，尽管疲劳在比赛期间和赛季结束时会累积，但前交叉韧带（ACL）损伤并未显著增加，周围疲劳引起的肌肉无力可能起关键作用。本研究的目的是系统评价不同的周围疲劳干预措施对着陆任务期间与ACL损伤风险相关的生物力学变量的影响。截至2024年9月，在Web of Science、Scopus、PubMed、EBSCO和Cochrane图书馆这五个数据库中进行了系统检索。使用证据分类系统对下肢生物力学变化的证据进行分级。共纳入12项研究，涉及217名参与者（105名男性，112名女性）。这些研究检查了9种周围疲劳方案、14种运动学变量和16种动力学变量。在所审查的14种运动学变量中，有力证据表明，在股四头肌和腘绳肌周围疲劳方案后，着陆任务期间垂直地面反作用力（vGRF）峰值时膝关节内旋角度增加（效应大小=0.24-0.68）。对于所审查的16种动力学变量，有力证据仅表明，在股四头肌和腘绳肌周围疲劳方案后，着陆任务期间vGRF峰值降低（效应大小=0.12-0.32）。总之，我们发现只有两种周围疲劳干预措施有证据支持，而大多数运动学和动力学变量显示出相互矛盾的结果，这突出了进一步研究的必要性。这些改进将有助于阐明当前的神经肌肉ACL损伤预防计划是否需要调整，以适应周围疲劳带来的生物力学变化。clinicaltrials.gov，标识符CRD42024593839。
