Neza Alice, Birungi Francine, Remera Eric, Hakizayezu François, Ntaganira Joseph
Department of Epidemiology and Biostatistics, School of Public Health, College of Medicine and Health Sciences, University of Rwanda,Kigali, Rwanda.
HIV/AIDS and STIs Diseases Division, Rwanda Biomedical Centre, Kigali, Rwanda.
Rwanda J Med Health Sci. 2023 Mar 28;6(1):43-52. doi: 10.4314/rjmhs.v6i1.6. eCollection 2023 Mar.
Optimal viral load suppression results from good adherence to treatment. The viral load suppression advantages include the reduction of virus transmission. In Rwanda, however, viral load suppression among adolescents and young adults has been proven relatively low than in other age groups.
To assess the factors associated with viral load suppression among adolescent and young adults in Ngororero district, Rwanda.
A cross sectional study that included 151 adolescents and young adults aged from 15 to 24 years was conducted in Ngororero district. Data were entered in Epi-Info version 7 software and analyzed using STATA15.
Females and males were 68% and 32% respectively. Sixty percent of the participants were aged20-24 years. Multivariable analysis revealed the factors associated with viral load suppression: Ubudehe category 2, P= 0.016, AOR = 6.6, CI [1.4, 31.1]; ubudehe category 3, P= 0.004, AOR = 8.9, CI [2.01,39.8]; spending between 5 to 9 years on ART, P= 0.022, AOR = 0.16 [CI0.03, 0.89;) and often forget to take medication, P= 0.011, AOR = 0.35, CI [0.13, 0.97.].
Viral load suppression among adolescents and young adults was low. Improving socio-economic conditions of adolescents and young adults, as well as provision of continuous counselling to them during their whole treatment life can improve significantly their adherence.
良好的治疗依从性可实现最佳的病毒载量抑制。病毒载量抑制的优势包括减少病毒传播。然而，在卢旺达，青少年和青年的病毒载量抑制率被证明低于其他年龄组。
评估卢旺达恩戈罗雷罗区青少年和青年中与病毒载量抑制相关的因素。
在恩戈罗雷罗区进行了一项横断面研究，纳入了151名年龄在15至24岁之间的青少年和青年。数据录入Epi-Info 7软件，并使用STATA15进行分析。
女性和男性分别占68%和32%。60%的参与者年龄在20 - 24岁之间。多变量分析揭示了与病毒载量抑制相关的因素：乌布德赫2类，P = 0.016，调整后比值比（AOR）= 6.6，置信区间（CI）[1.4, 31.1]；乌布德赫3类，P = 0.004，AOR = 8.9，CI [2.01, 39.8]；接受抗逆转录病毒治疗5至9年，P = 0.022，AOR = 0.16 [CI 0.03, 0.89]；经常忘记服药，P = 0.011，AOR = 0.35，CI [0.13, 0.97]。
青少年和青年中的病毒载量抑制率较低。改善青少年和青年的社会经济状况，以及在整个治疗过程中为他们提供持续的咨询服务，可以显著提高他们（对治疗的）依从性。
