实验性脊髓损伤中的血管通透性
Vascular permeability in experimental spinal cord injury.
作者信息
Hsu C Y, Hogan E L, Gadsden R H, Spicer K M, Shi M P, Cox R D
出版信息
J Neurol Sci. 1985 Oct;70(3):275-82. doi: 10.1016/0022-510x(85)90169-8.
PMID:4056823
Abstract
Following spinal cord injury in rats there was a time-dependent change of vascular permeability as reflected by extravasation of 125I-labelled serum albumin. The change of vascular permeability correlated with tissue calcium and water accumulation suggesting that cord exposure to plasma calcium as a consequence of vascular injury may contribute to the progressive post-traumatic cord necrosis.
摘要
大鼠脊髓损伤后，125I标记的血清白蛋白外渗反映出血管通透性随时间变化。血管通透性的变化与组织钙和水的蓄积相关，提示因血管损伤导致脊髓暴露于血浆钙可能促成创伤后脊髓坏死的进展。
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