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一例外用米诺地尔引起的接触性过敏性皮炎

A Case of Contact Allergic Dermatitis to Topical Minoxidil.

作者信息

BinJadeed Hessah, Almudimeegh Almuntsrbellah M, Alomran Shadn A, Alshathry Abdullah H

机构信息

Dermatology, King Khalid University Hospital, Riyadh, SAU.

College of Medicine, King Saud University, Riyadh, SAU.

出版信息

Cureus. 2021 Jan 5;13(1):e12510. doi: 10.7759/cureus.12510.

DOI:10.7759/cureus.12510
PMID:33564516
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7861115/
Abstract

Coincidental findings of hypertrichosis in patients on minoxidil led to the development of a topical minoxidil formulation which has been approved by the Food and Drug Administration for the treatment of female pattern hair loss, the most common cause for hair loss in women. The most common side effect of topical minoxidil is irritant contact dermatitis with the typical symptoms of itching and scaling. Most commonly, these symptoms are a result of an allergic reaction to propylene glycol, or less commonly, to minoxidil itself. We present a case of a 27-year-old woman who developed facial swelling following allergic contact dermatitis to minoxidil 5% foam.

摘要

米诺地尔治疗患者中偶然发现多毛症,促使了局部用米诺地尔制剂的研发,该制剂已获美国食品药品监督管理局批准,用于治疗女性型脱发,这是女性脱发最常见的原因。局部用米诺地尔最常见的副作用是刺激性接触性皮炎,典型症状为瘙痒和脱屑。这些症状通常是对丙二醇过敏反应的结果,较少情况下是对米诺地尔本身过敏。我们报告一例27岁女性病例,该患者在接触5%米诺地尔泡沫发生过敏性接触性皮炎后出现面部肿胀。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/802d/7861115/dbe8aacb7e38/cureus-0013-00000012510-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/802d/7861115/dbe8aacb7e38/cureus-0013-00000012510-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/802d/7861115/dbe8aacb7e38/cureus-0013-00000012510-i01.jpg

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Int Arch Allergy Immunol. 2016;169(3):163-70. doi: 10.1159/000445835. Epub 2016 Apr 22.
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Frontal Edema Due to Topical Application of %5 Minoxidil Solution Following Mesotherapy Injections.中胚层疗法注射后外用5%米诺地尔溶液引起的额部水肿
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