Bala Nathan, Croft Rodney J, McIntosh Robert L, Iskra Steve, Frankland John V, McKenzie Raymond J, Deng Chao
University of Wollongong, School of Medical, Indigenous and Health Science, and Molecular Horizons, Wollongong, NSW, Australia.
Wollongong Bioelectromagnetics Laboratory, Wollongong, NSW, Australia.
Bioelectromagnetics. 2025 Jul;46(5):e70013. doi: 10.1002/bem.70013.
The present study investigated the core body temperature (CBT) response of free-moving adult male and female Sprague Dawley rats, during and following a 3-h exposure to 1.95 GHz radiofrequency electromagnetic fields (RF-EMFs) within custom-built reverberation chambers, using temperature capsules implanted within the intraperitoneal cavity and data transmitted via radiotelemetry. Comparing RF-EMF exposures (at Whole-Body Average-Specific Absorption Rate [WBA-SAR] levels of 0.1, 0.4, and 4 W/kg) to the sham exposed condition, we identified a statistically significant peak increase in CBT after 26 min of RF-EMF exposure at 4 W/kg (+0.49°C), but not in the 0.1 or 0.4 W/kg conditions at the same timepoint. In the last 30 min of the RF-EMF exposure, temperature was significantly increased in both the 4 W/kg (0.62°C) and 0.4 W/kg (0.14°C) conditions, but not 0.1 W/kg, when compared to sham. After 20 min following cessation of exposure, post temperature was still significantly higher in the 4 W/kg condition when compared to the sham (0.37°C), but not in either 0.1 or 0.4 W/kg. Based on our findings, it is apparent that rats can effectively compensate for increased thermal loads of up to 4 W/kg as the maximum temperature rise was substantially lower than 1°C. In addition, the elevated CBT during exposure in the 4 W/kg condition was significantly reduced immediately after exposure cessation, indicating that measures of CBT following RF-EMF exposure cessation may not reflect maximum RF-EMF-mediated changes in the CBT of rats. Bioelectromagnetics. 00:00-00, 2025. © 2025 Bioelectromagnetics Society.
本研究使用植入腹腔内的温度胶囊并通过无线电遥测传输数据，调查了自由活动的成年雄性和雌性斯普拉格-道利大鼠在定制混响室内暴露于1.95 GHz射频电磁场（RF-EMF）3小时期间及之后的核心体温（CBT）反应。将RF-EMF暴露（全身平均比吸收率[WBA-SAR]水平为0.1、0.4和4 W/kg）与假暴露条件进行比较，我们发现在4 W/kg的RF-EMF暴露26分钟后，CBT出现了具有统计学意义的峰值升高（+0.49°C），但在相同时间点的0.1或0.4 W/kg条件下未出现。在RF-EMF暴露的最后30分钟内，与假暴露相比，4 W/kg（0.62°C）和0.4 W/kg（0.14°C）条件下的体温均显著升高，但0.1 W/kg条件下未升高。暴露停止20分钟后，与假暴露相比，4 W/kg条件下的体温仍显著更高（0.37°C），但0.1或0.4 W/kg条件下未出现这种情况。根据我们的研究结果，很明显大鼠可以有效补偿高达4 W/kg的增加热负荷，因为最高温度升高显著低于1°C。此外，在4 W/kg条件下暴露期间升高的CBT在暴露停止后立即显著降低，这表明在RF-EMF暴露停止后测量CBT可能无法反映大鼠CBT中RF-EMF介导的最大变化。《生物电磁学》。2025年00:00 - 00。© 2025生物电磁学协会。
