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关键建模假设对牙种植体初期稳定性有限元预测的影响。

Influence of key modeling assumptions on the finite element prediction of dental implant primary stability.

作者信息

Vautrin Antoine, Zysset Philippe, Varga Peter

机构信息

AO Research Institute Davos, Switzerland; Graduate School for Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland.

ARTORG Center for Biomedical Engineering Research, University of Bern, Bern, Switzerland.

出版信息

Comput Biol Med. 2025 Sep;195:110587. doi: 10.1016/j.compbiomed.2025.110587. Epub 2025 Jun 25.

Abstract

The clinical success of a dental implant is dependent on its post-operative primary stability. Finite element (FE) modeling of the bone-implant construct stability has gained interest, but the impact of modeling assumptions on outcomes remains uncertain. This sensitivity study examines the effect of three key parameters - bone homogeneity, bone-implant contact definition and implant properties - on the load-bearing capacity of the bone-implant construct. A validated FE model served as a reference, replicating the experimental loading of dental implants inserted into 30 human jawbone biopsies from a previous study. This base model incorporated heterogeneous bone, contact with friction at the bone-implant interface, and a rigid implant. Model variations were generated by independently changing each parameter, the alternative modeling choices being homogeneous bone, a tied interface and an elastic implant, respectively. Model accuracy was evaluated based on correlation and root mean square error with the experimental ultimate force. Homogeneous bone properties led to an underestimation of the ultimate load, while a tied interface overestimated it. Modeling homogeneous bone or a tied interface resulted in lower correlations with experimental ultimate force (R = 0.61 and 0.70, respectively), compared to the base model (R = 0.81). Implant material (elastic vs. rigid) impacted the initial stiffness but not the load-bearing capacity. Employing heterogeneous bone properties and defining the interface as a contact with friction is recommended to accurately model primary stability of bone-implant constructs. In particular, an overestimation of the primary stability could lead to suboptimal implant design, placement or biased decisions.

摘要

牙种植体的临床成功取决于其术后的初始稳定性。骨-种植体结构稳定性的有限元(FE)建模已引起关注,但建模假设对结果的影响仍不确定。这项敏感性研究考察了三个关键参数——骨的均匀性、骨-种植体接触定义和种植体特性——对骨-种植体结构承载能力的影响。一个经过验证的有限元模型作为参考,复制了先前研究中插入30例人类颌骨活检样本中的牙种植体的实验加载情况。这个基础模型纳入了异质骨、骨-种植体界面处有摩擦的接触以及一个刚性种植体。通过分别独立改变每个参数来生成模型变体,替代的建模选择分别是均质骨、绑定界面和弹性种植体。基于与实验极限力的相关性和均方根误差来评估模型准确性。均质骨特性导致对极限载荷的低估,而绑定界面则导致高估。与基础模型(R = 0.81)相比,对均质骨或绑定界面进行建模与实验极限力的相关性较低(分别为R = 0.61和0.70)。种植体材料(弹性与刚性)影响初始刚度,但不影响承载能力。建议采用异质骨特性并将界面定义为有摩擦的接触,以准确模拟骨-种植体结构的初始稳定性。特别是,对初始稳定性的高估可能导致种植体设计、植入欠佳或决策有偏差。

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