Arena J G, Blanchard E B, Andrasik F, Appelbaum K, Myers P E
J Psychosom Res. 1985;29(4):427-41. doi: 10.1016/0022-3999(85)90029-7.
Twenty-eight chronic headache sufferers of three headache types (migraine, tension and combined migraine-tension) selected on the basis of explicit inclusion and exclusion criteria and matched on five demographic characteristics were assessed in a headache and non-headache state on a number of psychophysiological measures (frontalis, forearm and neck EMG; cephalic vasomotor response; hand surface temperature; heart rate and skin resistance level) and a number of stimulus conditions (baseline, self-control, cognitive and physical stressors). Results indicated no significant differences between the three headache groups or headache states on any measure during baseline condition. Analyses of post-stress adaptation periods led to the area of most significant differences, with a number of findings lending support for Sternbach's inadequate homeostatic responding hypothesis of migraine, but not tension, headache. No support was found for the sustained levels of muscle tension hypothesis of the etiology of tension headache. Implications for the etiology and treatment of headache are discussed.
根据明确的纳入和排除标准选取了28名患有三种头痛类型（偏头痛、紧张性头痛以及偏头痛 - 紧张性混合头痛）的慢性头痛患者，并在五个人口统计学特征上进行了匹配。对这些患者在头痛和非头痛状态下进行了多项心理生理指标（额肌、前臂和颈部肌电图；头部血管舒缩反应；手部表面温度；心率和皮肤电阻水平）以及多种刺激条件（基线、自我控制、认知和身体应激源）的评估。结果表明，在基线条件下，三个头痛组或头痛状态在任何指标上均无显著差异。对应激后适应期的分析导致了差异最为显著的领域，多项研究结果支持了斯特恩巴赫关于偏头痛而非紧张性头痛的内稳态反应不足假说。未发现支持紧张性头痛病因的肌肉紧张持续水平假说的证据。文中讨论了这些结果对头痛病因和治疗的启示。
