Dini Irene, Mancusi Andrea, Seccia Serenella
Department of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, 80131 Napoli, Italy.
Department of Food Microbiology, Istituto Zooprofilattico Sperimentale del Mezzogiorno, Via Salute 2, 80055 Portici, Italy.
Molecules. 2025 Jun 10;30(12):2535. doi: 10.3390/molecules30122535.
This review examines how plastics break down into dangerous pollutants like microplastics, nanoplastics, and persistent organic pollutants (POPs) that can contaminate the environment, make their way into the human food chain, and provoke toxicological effects in humans. According to the reviewed literature, new biomarkers associated with their exposure should be identified, and new methods for detecting them in the environment and in food should be developed and validated. It would also be interesting to improve research on the interaction between micro- and nanoplastics and human cells, their impact on DNA, and their long-term health effects. Promoting sustainable practices and adherence to the 3R strategies (reduce, reuse, and recycle) to transform hazardous waste into valuable resources is crucial to protecting public health from dangerous contaminants as we wait on the development of new diagnostic methods and more stringent legislation.
本综述探讨了塑料如何分解为微塑料、纳米塑料和持久性有机污染物(POPs)等危险污染物,这些污染物会污染环境,进入人类食物链,并对人类产生毒理学影响。根据综述文献,应识别与它们暴露相关的新生物标志物,并开发和验证在环境和食品中检测它们的新方法。改进对微塑料和纳米塑料与人类细胞之间相互作用、它们对DNA的影响以及它们的长期健康影响的研究也将是有趣的。在等待新诊断方法和更严格立法的发展过程中,推广可持续做法并坚持3R策略(减少、再利用和回收),将危险废物转化为有价值的资源,对于保护公众健康免受危险污染物的侵害至关重要。