Duncan J J, Farr J E, Upton S J, Hagan R D, Oglesby M E, Blair S N
JAMA. 1985 Nov 8;254(18):2609-13.
The effects of a 16-week aerobic exercise program on blood pressure and plasma catecholamine levels were evaluated in 56 patients with baseline diastolic blood pressure of 90 to 140 mm Hg. The exercise group significantly improved their physical fitness, and reduced systolic and diastolic blood pressures, compared with controls. To evaluate the relationship between exercise, blood pressure, and plasma catecholamine values, the exercise group was further divided into hyperadrenergic and normoadrenergic subgroups. Reductions in systolic pressures were 6.3 mm Hg, 10.3 mm Hg, and 15.5 mm Hg for control, normoadrenergic, and hyperadrenergic groups, respectively. Diastolic changes were similar and also significant. Within the hyperadrenergic group, changes in blood pressures were associated with changes in values for plasma catecholamines following training. We conclude that an aerobic exercise program reduces blood pressure, which is at least partially mediated by changes in plasma catecholamine levels.
在56名基线舒张压为90至140毫米汞柱的患者中，评估了为期16周的有氧运动计划对血压和血浆儿茶酚胺水平的影响。与对照组相比，运动组的体能显著改善，收缩压和舒张压降低。为了评估运动、血压和血浆儿茶酚胺值之间的关系，运动组进一步分为高肾上腺素能亚组和正常肾上腺素能亚组。对照组、正常肾上腺素能组和高肾上腺素能组的收缩压分别降低6.3毫米汞柱、10.3毫米汞柱和15.5毫米汞柱。舒张压变化相似且也具有显著性。在高肾上腺素能组中，训练后血压变化与血浆儿茶酚胺值变化相关。我们得出结论，有氧运动计划可降低血压，这至少部分是由血浆儿茶酚胺水平的变化介导的。
