乳腺癌亚型：临床病理特征与治疗考量
Breast Cancer Subtypes: Clinicopathologic Features and Treatment Considerations.
作者信息
Cobb Adrienne N, Czaja Rebecaa, Jorns Julie, Cortina Chandler S
机构信息
Division of Surgical Oncology, Department of Surgery, Medical College of Wisconsin, 8701 Watertown Plank Rd., Milwaukee, WI 53226, USA.
Medical College of Wisconsin Cancer Center, Milwaukee, WI, USA.
出版信息
Curr Breast Cancer Rep. 2024 Jun;16(2):150-160. doi: 10.1007/s12609-024-00541-6. Epub 2024 Mar 26.
PURPOSE OF REVIEW
The purpose of this review is to provide an overview of ten unique breast cancer subtypes and their clinicopathologic features and treatment implications.
RECENT FINDINGS
Recent findings show that while many subtypes (mucinous, papillary, tubular, apocrine) have favorable biology, with better overall survival than invasive ductal carcinoma, some (metaplastic, adenoid cystic) are more aggressive portending worse prognosis for patients.
SUMMARY
The differences in histology represented in these breast cancer subtypes often impacts biology, behavior, and prognosis. Due to their rarity, additional research is needed to implement clear treatment protocols for each subtype.
综述目的
本综述旨在概述十种独特的乳腺癌亚型及其临床病理特征和治疗意义。
最新发现
最新研究结果表明，虽然许多亚型（黏液性、乳头状、管状、大汗腺样）生物学行为良好，总体生存率优于浸润性导管癌，但有些亚型（化生性、腺样囊性）侵袭性更强，预示患者预后更差。
总结
这些乳腺癌亚型在组织学上的差异通常会影响生物学行为和预后。由于它们较为罕见，需要更多研究来为每种亚型制定明确的治疗方案。
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