Masionis Povilas, Bobina Rokas, Utkus Simonas, Martinaitytė Raminta, Uvarovas Valentinas, Šatkauskas Igoris
Clinic of Rheumatology, Orthopaedic Traumatology and Reconstructive Surgery, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University; Centre of Orthopedics and Traumatology, Vilnius Republican University Hospital, Vilnius, Lithuania.
Geriatr Orthop Surg Rehabil. 2025 Jun 25;16:21514593251352336. doi: 10.1177/21514593251352336. eCollection 2025.
As the global population ages, hip fracture importance will increase. The high postoperative mortality and morbidity necessitate tools for accurate risk assessment to aid surgical decisions and inform patients and families. This study aimed to compare and validate ACS NSQIP, Nottingham hip fracture risk calculators, and C reactive protein/albumin ratio in predicting complications and 30 day mortality. 583 patients over the 65 years old who sustained hip fracture from simple fall and underwent surgical treatment for hip fracture were included in prospective study. Each patient was evaluated by ACS NSQIP and Nottingham hip fracture risk calculators and C reactive protein/albumin ratio was calculated from preoperative values. Patients were followed up for 30 days and all the complications were recorded. ACS NSQIP and Nottingham hip fracture score showed AUC of .724 and .731 respectively. C reactive protein/albumin ratio performed less and showed AUC of .623 that is defined as poor predictor for 30 day mortality. Furthermore, in terms of predicting any complication, ACS NSQIP showed AUC of .645, Nottingham hip fracture score of .611 and C reactive protein/albumin ratio of .594. Nottingham hip fracture score than compared to ACS NSQIP yielded lower average of mortality rates (5.4% compared to 7.9%) in contrast of study findings of 8.1%. None of the ACS NSQIP scale predictive complication showed acceptable performance. When adjusted for fracture type, Nottingham hip fracture score showed .858 AUC in predicting 30 day mortality in femoral neck fractures. We recommend Nottingham fracture risk calculator use for 30 day mortality risk assessment in femoral neck fractures. In hip fractures combined-none of models showed strong discrimination. In our cohort C reactive protein/albumin ratio showed poor prognostic values in terms of mortality and complications.
随着全球人口老龄化,髋部骨折的重要性将日益增加。术后的高死亡率和发病率使得准确的风险评估工具成为必要,以辅助手术决策并告知患者及其家属。本研究旨在比较和验证美国外科医师协会国家外科质量改进计划(ACS NSQIP)、诺丁汉髋部骨折风险计算器以及C反应蛋白/白蛋白比值在预测并发症和30天死亡率方面的作用。一项前瞻性研究纳入了583名65岁以上因简单跌倒导致髋部骨折并接受手术治疗的患者。每位患者均接受ACS NSQIP和诺丁汉髋部骨折风险计算器评估,并根据术前值计算C反应蛋白/白蛋白比值。对患者进行30天随访并记录所有并发症。ACS NSQIP和诺丁汉髋部骨折评分的曲线下面积(AUC)分别为0.724和0.731。C反应蛋白/白蛋白比值表现较差,AUC为0.623,被定义为30天死亡率的不良预测指标。此外,在预测任何并发症方面,ACS NSQIP的AUC为0.645,诺丁汉髋部骨折评分为0.611,C反应蛋白/白蛋白比值为0.594。与ACS NSQIP相比,诺丁汉髋部骨折评分得出的平均死亡率较低(分别为5.4%和7.9%),而研究结果为8.1%。ACS NSQIP量表预测并发症的表现均未达到可接受水平。在对骨折类型进行校正后,诺丁汉髋部骨折评分在预测股骨颈骨折30天死亡率时的AUC为0.858。我们建议使用诺丁汉骨折风险计算器评估股骨颈骨折的30天死亡风险。在髋部骨折合并其他情况时,没有一个模型显示出很强的区分能力。在我们的队列中,C反应蛋白/白蛋白比值在死亡率和并发症方面显示出较差的预后价值。