Liu Yinan, Chen Xiaoyong
Department of Ophthalmology, Peking University Third Hospital, Beijing, China.
Front Med (Lausanne). 2025 Jun 12;12:1554832. doi: 10.3389/fmed.2025.1554832. eCollection 2025.
During cataract phacoemulsification surgery, the Alcon Centurion with Active Sentry can achieve a more stable anterior chamber, which allows a lower intraocular pressure (IOP) setting than Centurion under gravity mode. In this randomized controlled trial, we compared these two systems' impact on high myopia patients' macular blood perfusion under different IOP settings. To evaluate intra-op and post-op clinical performance of the Alcon Centurion with Active Sentry and under gravity mode in cataract patients with eye axial lengths > 26 mm.
Fifty-two eyes of 43 cataract patients with axial lengths > 26 mm were enrolled and randomly divided into the active fluidics system (AFS) group using a Centurion Active Sentry handpiece under 30 mmHg IOP setting (26 eyes) and the gravity fluidics system (GFS) group in gravity mode under 80 cmHO IOP setting (26 eyes). Intraoperative parameters, visual acuity, parafoveal macular vessel density and macular thickness were analyzed.
We observed no significant differences in best corrected visual acuity (BCVA), macular thickness, cumulative dissipated energy (CDE), total case time, as well as ophthalmic viscoelastic devices (OVDs) usage between the two groups. However, we found less pain complaints during surgeries and a more stable macular vessel density post-surgery in the AFS group than in the GFS group, implying higher intraoperative comfort levels and less retinal ischemia during cataract surgery using Centurion with Active Sentry under low IOP settings.
Owing to a lower IOP setting, Centurion Vision System with Active Sentry handpiece causes less retinal ischemia and pain perception during phacoemulsification for high myopia patients.
https://www.chictr.org.cn, identifier ChiCTR2400080875.
在白内障超声乳化手术中，配备主动哨兵系统的爱尔康Centurion超声乳化仪可实现更稳定的前房，这使得在眼压设置上比重力模式下的Centurion更低。在这项随机对照试验中，我们比较了这两种系统在不同眼压设置下对高度近视患者黄斑区血液灌注的影响。以评估配备主动哨兵系统的爱尔康Centurion超声乳化仪在眼轴长度>26mm的白内障患者中，在术中及术后的临床表现以及重力模式下的情况。
纳入43例眼轴长度>26mm的白内障患者的52只眼，随机分为主动流体控制系统（AFS）组，使用Centurion主动哨兵探头，眼压设置为30mmHg（26只眼），以及重力流体控制系统（GFS）组，采用重力模式，眼压设置为80cmHO（26只眼）。分析术中参数、视力、黄斑中心凹旁血管密度和黄斑厚度。
我们观察到两组之间在最佳矫正视力（BCVA）、黄斑厚度、累积消散能量（CDE）、总手术时间以及眼科粘弹性装置（OVDs）使用方面无显著差异。然而，我们发现AFS组在手术期间的疼痛主诉较少，且术后黄斑血管密度比GFS组更稳定，这意味着在低眼压设置下使用配备主动哨兵系统的Centurion进行白内障手术时，术中舒适度更高且视网膜缺血更少。
由于眼压设置较低，配备主动哨兵探头的Centurion视觉系统在高度近视患者的超声乳化手术中引起的视网膜缺血和疼痛感知较少。
