Masuda F, Yoshida M, Kondo N, Takahashi T, Kondo I, Furuta N
Gan No Rinsho. 1985 Aug;31(10):1293-6.
Fever developed in 65 (37.8%) out of 172 patients with renal cell carcinoma, being the third most frequent symptom following hematuria and renal mass. Patients who developed fever were associated with symptoms such as palpable renal mass, general malaise anorexia, weight loss, acceleration in ESR, liver dysfunctions and an increase in alpha 2-globulin significantly more frequently than those who did not. Histologically also, high graded cases were more common with a significant. Moreover, the prognosis was significantly more poor.
172例肾细胞癌患者中有65例（37.8%）出现发热，发热是继血尿和肾肿块之后第三常见的症状。出现发热的患者比未出现发热的患者更频繁地伴有可触及的肾肿块、全身不适、厌食、体重减轻、血沉加快、肝功能障碍以及α2球蛋白升高。在组织学上，高分级病例也更常见，且差异显著。此外，预后明显更差。
