Suppr超能文献

微生物组、生态失调与益生菌在各种疾病中的应用

Microbiome, dysbiosis and use of probiotics in various diseases.

作者信息

Tüsüz Önata Ece, Özdemir Öner

机构信息

Division of Allergy and Immunology, Department of Pediatrics, Sakarya Research and Training Hospital, Sakarya University, Faculty of Medicine, Sakarya 54100, Türkiye.

出版信息

World J Virol. 2025 Jun 25;14(2):99574. doi: 10.5501/wjv.v14.i2.99574.

Abstract

The community of microorganisms that colonize certain areas of the human body is called microbiota. Microorganisms such as bacteria, fungi and viruses make up the microbiota. The sum of the genomes of these microorganisms and microorganisms refers to the microbiome. It has been shown that microbiota has important effects such as protecting the organ from pathogens, contributing to metabolic functions (such as vitamin synthesis, carbohydrate digestion) and providing immunoregulation. Dysbiosis refers to compositional and functional changes in the microbiota. At the beginning of the 21 century, numerous studies have investigated the human microbiota and its imbalance in relation to various diseases and found that dysbiosis is associated with many diseases. The aim of this mini-review article is to provide brief information about dysbiosis and its care and to raise awareness.

摘要

定植于人体特定部位的微生物群落被称为微生物群。细菌、真菌和病毒等微生物构成了微生物群。这些微生物的基因组总和被称为微生物组。研究表明,微生物群具有重要作用,如保护器官免受病原体侵害、促进代谢功能(如维生素合成、碳水化合物消化)以及提供免疫调节。生态失调是指微生物群的组成和功能发生变化。在21世纪初,众多研究调查了人类微生物群及其与各种疾病相关的失衡情况,并发现生态失调与许多疾病有关。这篇小型综述文章的目的是提供有关生态失调及其护理的简要信息并提高认识。

相似文献

3
Synbiotics, prebiotics and probiotics for people with chronic kidney disease.慢性肾脏病患者的合生菌、益生元和益生菌。
Cochrane Database Syst Rev. 2023 Oct 23;10(10):CD013631. doi: 10.1002/14651858.CD013631.pub2.
5
Radiation-induced injury and the gut microbiota: insights from a microbial perspective.辐射诱导损伤与肠道微生物群:从微生物视角的见解
Therap Adv Gastroenterol. 2025 Jun 16;18:17562848251347347. doi: 10.1177/17562848251347347. eCollection 2025.
6
Single-incision sling operations for urinary incontinence in women.女性尿失禁的单切口吊带手术
Cochrane Database Syst Rev. 2017 Jul 26;7(7):CD008709. doi: 10.1002/14651858.CD008709.pub3.
7
Fecal microbiota transplantation in allergic diseases.粪便微生物群移植在过敏性疾病中的应用。
World J Methodol. 2025 Jun 20;15(2):101430. doi: 10.5662/wjm.v15.i2.101430.

本文引用的文献

2
Role of Intestinal Microbes in Chronic Liver Diseases.肠道微生物在慢性肝病中的作用。
Int J Mol Sci. 2022 Oct 21;23(20):12661. doi: 10.3390/ijms232012661.
3
Gut microbiota, inflammatory bowel disease and colorectal cancer.肠道微生物群、炎症性肠病和结直肠癌。
World J Gastroenterol. 2022 Aug 14;28(30):4053-4060. doi: 10.3748/wjg.v28.i30.4053.
6
Human gut microbiota/microbiome in health and diseases: a review.人类肠道微生物组/微生物群在健康和疾病中的作用:综述。
Antonie Van Leeuwenhoek. 2020 Dec;113(12):2019-2040. doi: 10.1007/s10482-020-01474-7. Epub 2020 Nov 2.
7
Hepatic Stellate Cells and Hepatocarcinogenesis.肝星状细胞与肝癌发生
Front Cell Dev Biol. 2020 Aug 5;8:709. doi: 10.3389/fcell.2020.00709. eCollection 2020.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验