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本文引用的文献

1
Association of vaginal dysbiosis and gestational diabetes mellitus with adverse perinatal outcomes.阴道微生态失调与妊娠期糖尿病和不良围产期结局的关联。
Int J Gynaecol Obstet. 2022 Jul;158(1):70-78. doi: 10.1002/ijgo.13945. Epub 2021 Oct 18.
2
Association of gestational diabetes mellitus and abnormal vaginal flora with adverse pregnancy outcomes.妊娠期糖尿病及阴道菌群异常与不良妊娠结局的关联
Medicine (Baltimore). 2018 Aug;97(34):e11891. doi: 10.1097/MD.0000000000011891.
3
Risk of Vaginal Infections at Early Gestation in Patients with Diabetic Conditions during Pregnancy: A Retrospective Cohort Study.妊娠期糖尿病患者孕早期阴道感染风险:一项回顾性队列研究
PLoS One. 2016 May 11;11(5):e0155182. doi: 10.1371/journal.pone.0155182. eCollection 2016.
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Diabetes in pregnancy.妊娠期糖尿病
Best Pract Res Clin Obstet Gynaecol. 2015 Jul;29(5):685-99. doi: 10.1016/j.bpobgyn.2015.04.009. Epub 2015 Apr 28.
5
Vulvovaginal candidosis.外阴阴道念珠菌病
Lancet. 2007 Jun 9;369(9577):1961-71. doi: 10.1016/S0140-6736(07)60917-9.
6
Activity of hydrolytic enzymes in fungi isolated from diabetic pregnant women: is there any relationship between fungal alkaline and acid phosphatase activity and glycemic control?从糖尿病孕妇体内分离出的真菌中水解酶的活性:真菌碱性磷酸酶和酸性磷酸酶活性与血糖控制之间是否存在关联?
APMIS. 2004 Jun;112(6):374-83. doi: 10.1111/j.1600-0463.2004.apm1120608.x.
7
Prevalence of fungi in the vagina, rectum and oral cavity in pregnant diabetic women: relation to gestational age and symptoms.妊娠糖尿病妇女阴道、直肠和口腔中真菌的患病率:与孕周和症状的关系。
Acta Obstet Gynecol Scand. 2004 Mar;83(3):251-6. doi: 10.1111/j.0001-6349.2004.0361.x.
8
Gestational diabetes mellitus.妊娠期糖尿病
Diabetes Care. 2003 Jan;26 Suppl 1:S103-5. doi: 10.2337/diacare.26.2007.s103.
9
Gestational diabetes mellitus.妊娠期糖尿病
Clin Lab Med. 2001 Mar;21(1):173-92.
10
[Bacterial vaginosis. Epidemiology and risk factors].[细菌性阴道病。流行病学与危险因素]
Srp Arh Celok Lek. 2000 Jan-Feb;128(1-2):29-33.

阴道感染与妊娠期糖尿病之间的关系。

Relationship between vaginal infections and gestational diabetes.

作者信息

Ahmadi Amjad, Abdolmaleki Noushin, Roshani Daem, Farhadifar Fariba, Ramazanzadeh Rashid, Shahgheibi Sholeh, Zarei Mozhdeh, Shakiba Nadia, Nikkhoo Bahram

机构信息

Social Determinants of Health Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran.

Department of Microbiology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.

出版信息

Caspian J Intern Med. 2025 Mar 11;16(2):263-267. doi: 10.22088/cjim.16.2.263. eCollection 2025 Spring.

DOI:10.22088/cjim.16.2.263
PMID:40575753
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12188890/
Abstract

BACKGROUND

Gestational diabetes is defined as glucose intolerance with variable severity which starts or is first diagnosed during pregnancy. Globally on the rise, this health condition is one of the most common complications of pregnancy. Pregnant women with diabetes are at high risk of infection because high blood sugar levels provide food for many infections, including yeast, making it easier for the yeast to grow. This study aimed to examine the relationship between vaginal infections and gestational diabetes.

METHODS

This study enrolled 300 pregnant women with gestational diabetes as the patient group and 300 pregnant women without gestational diabetes as the control group. The research tool in this study was a questionnaire and performing a warm and wet slide staining test on the vaginal swab sample.

RESULTS

The mean age was 31.97±6.02 in the women with gestational diabetes and 30.98± 6.80 in the women without gestational diabetes. Smoking was zero in both groups. The frequency of vaginal infection was 34 (11.3%) in the patient group and 26(8.7%) in the control group. vaginal infections showed no significant association with gestational diabetes.

CONCLUSION

Despite its high prevalence, vaginal infections showed no significant association with gestational diabetes. Still, the high prevalence of infection in the two groups demands more attention from the healthcare system and obstetrician-gynecologists to check the infection before and after pregnancy.

摘要

背景

妊娠期糖尿病被定义为在孕期开始或首次被诊断出的、严重程度各异的葡萄糖不耐受。这种健康状况在全球范围内呈上升趋势,是妊娠最常见的并发症之一。糖尿病孕妇感染风险高,因为高血糖水平为包括酵母菌在内的多种感染提供了养分,使酵母菌更易生长。本研究旨在探讨阴道感染与妊娠期糖尿病之间的关系。

方法

本研究纳入300例妊娠期糖尿病孕妇作为患者组,300例非妊娠期糖尿病孕妇作为对照组。本研究的研究工具是一份问卷,并对阴道拭子样本进行湿片染色试验。

结果

妊娠期糖尿病女性的平均年龄为31.97±6.02岁,非妊娠期糖尿病女性的平均年龄为30.98±6.80岁。两组吸烟率均为零。患者组阴道感染发生率为34例(11.3%),对照组为26例(8.7%)。阴道感染与妊娠期糖尿病无显著关联。

结论

尽管阴道感染患病率高,但与妊娠期糖尿病无显著关联。尽管如此,两组感染的高患病率仍需要医疗系统和妇产科医生给予更多关注,以便在孕前和孕后检查感染情况。