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外阴阴道念珠菌病

Vulvovaginal candidosis.

作者信息

Sobel Jack D

机构信息

Department of Medicine, Wayne State University School of Medicine, Detroit, MI, USA.

出版信息

Lancet. 2007 Jun 9;369(9577):1961-71. doi: 10.1016/S0140-6736(07)60917-9.

Abstract

Despite therapeutic advances, vulvovaginal candidosis remains a common problem worldwide, affecting all strata of society. Understanding of anti-candida host defence mechanisms in the vagina has developed slowly and, despite a growing list of recognised risk factors, a fundamental grasp of pathogenic mechanisms continues to elude us. The absence of rapid, simple, and inexpensive diagnostic tests continues to result in both overdiagnosis and underdiagnosis of vulvovaginal candidosis. I review the epidemiology and pathogenesis of this infection, and also discuss management strategies.

摘要

尽管在治疗方面取得了进展,但外阴阴道念珠菌病在全球范围内仍然是一个常见问题,影响着社会各阶层。人们对阴道中抗念珠菌宿主防御机制的认识发展缓慢,而且尽管已识别的风险因素越来越多,但我们仍未完全掌握其致病机制。缺乏快速、简单且廉价的诊断测试继续导致外阴阴道念珠菌病的过度诊断和诊断不足。我将综述这种感染的流行病学和发病机制,并讨论管理策略。

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