Whole antilymphocyte serum: a potent safe immunosuppressive agent for intravenous use in man.
作者信息
Levey R H, Parkman R
出版信息
Transplant Proc. 1977 Mar;9(1):1019-22.
PMID:405764
Abstract
Fifty-one renal and marrow graft recipients have been treated with whole, absorbed rabbit anti-human-lymphocyte serum. Such sera are potent nontoxic immunosuppressive agents. Preexisting sensitivity can be erased, and early rejection episodes are essentially eliminated. Prolonged treatment is necessary and safe, and it ensures a sustained depression in circulating T cells. Adaptation between kidney graft and host then occurs, so that the combination of prednisone and Imuran alone can sustain graft viability.
摘要
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Whole antilymphocyte serum: a potent safe immunosuppressive agent for intravenous use in man.
Transplant Proc. 1977 Mar;9(1):1019-22.
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