Gieldanowski J, Blaszczyk B, Szymaniec S, Ludwikowska A
Arch Immunol Ther Exp (Warsz). 1977;25(3):367-75.
Anti-inflammatory and immunosuppressive activity of equine antirabbit antithymocyte serum (ATS) was studied. ATS lowered serum levels of complement, inhibited cell proliferation in the granulation test, and prolonged survival of allogeneic skin grafts. Its action was accompanied by lymphopenia. Repeated immunization enhanced the activity of ATS in the graft rejection test and the drop in serum complement, and at the same time attenuated the effect on the granulation process and lowered proteolytic activity.
对马抗兔抗胸腺细胞血清（ATS）的抗炎和免疫抑制活性进行了研究。ATS降低了补体的血清水平，在肉芽形成试验中抑制细胞增殖，并延长了同种异体皮肤移植物的存活时间。其作用伴有淋巴细胞减少。重复免疫增强了ATS在移植物排斥试验中的活性以及血清补体的下降，同时减弱了对肉芽形成过程的影响并降低了蛋白水解活性。
