Development. 2025 Jun 15;152(12). doi: 10.1242/dev.205028. Epub 2025 Jun 27.
The temporal and spatial expression of Hox genes has been implicated in the establishment of the body plan. In their work, Yuuta Moriyama and colleagues find that spatiotemporally ordered expression of Hoxb genes regulates dynamic cell surface fluctuations during early gastrulation in zebrafish. To know more about their work, we spoke to the first and corresponding author, Yuuta Moriyama, Assistant Professor at Aoyama Gakuin University, Japan, and Carl-Philipp Heisenberg, Professor at the Institute of Science and Technology Austria (ISTA), Austria, where the project began.
Hox基因的时空表达与身体结构的建立有关。在他们的研究中，森山雄太及其同事发现，Hoxb基因在时空上有序表达，可调节斑马鱼原肠胚形成早期的动态细胞表面波动。为了进一步了解他们的研究工作，我们采访了该项目的第一作者兼通讯作者、日本青山学院大学助理教授森山雄太，以及项目起始地奥地利科学技术研究所（ISTA）的教授卡尔 - 菲利普·海森堡。
