Ozawa T, Nagoshi D, Tsubaki H, Tsugu Y
Nihon Heikatsukin Gakkai Zasshi. 1985 Feb;21(1):45-55. doi: 10.1540/jsmr1965.21.45.
To study the motility functions after transection and anastomosis of the intestinal tract, the interdigestive action potential was induced experimentally and observed in the small intestines of conscious fasted dogs. When the intestinal tract was transected, the frequency gradient of the basic electric rhythm was disturbed even in cases of subsequent anastomosis. Differences arose in the frequency as upper and lower part of anastomosis, and it did not return to normal. The spike potential which appeared with the building up of the basic electric rhythm was propagated to the distal intestine in a normal course after transection of the intestinal tract according to observations centered on propagation of the IMEC. The propagation velocity of the IMEC gradually drops from the proximal jejunum toward the terminal ileum in the nonmanipulated intestine, while in the intestine undergoing transection and anastomosis, the velocity of propagation was reduced by half in the area of anastomosis, and tended to be even lower in cases of a double section and two anastomoses of the distal intestine. However, the total elapsed time in the small intestine was not extended by much. A new electric complex appeared from the stump of the distal intestine when the intestine was subjected to transection, and a stimulation which is involved in the appearance of the spike potential was formed.
为研究肠道横断及吻合术后的运动功能，在清醒禁食犬的小肠中通过实验诱导并观察消化间期动作电位。当肠道被横断时，即使在后续吻合的情况下，基本电节律的频率梯度也会受到干扰。吻合口上下部的频率出现差异，且未恢复正常。以肠肌电复合体（IMEC）的传播为中心进行观察发现，在肠道横断后，随着基本电节律的建立而出现的锋电位会正常向远端肠段传播。在未处理的肠道中，IMEC的传播速度从空肠近端向回肠末端逐渐下降，而在进行横断及吻合的肠道中，吻合部位的传播速度降低一半，在远端肠道进行双重横断和两次吻合的情况下，传播速度往往更低。然而，小肠中的总耗时并未大幅延长。当肠道被横断时，远端肠段残端会出现新的电复合体，并形成与锋电位出现有关的刺激。
