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[消化间期移行性复合运动在肠道运动中的传播机制及神经调节机制的实验研究]

[Experimental investigations of the propagation mechanism and the nerve regulatory mechanism of the interdigestive migrating electric complex in intestinal movement].

作者信息

Ozawa T, Kawamura K, Kitahara S, Murakuni H, Deguchi H, Shimada N, Tsugu Y

机构信息

2nd Department of Surgery, Toho University, School of Medicine, Tokyo.

出版信息

Nihon Heikatsukin Gakkai Zasshi. 1990 Feb;26(1):9-20. doi: 10.1540/jsmr1965.26.9.

DOI:10.1540/jsmr1965.26.9
PMID:2255124
Abstract

Segments and Thirty-Vella type loops of the small intestine of dogs were prepared, and the excitation propagation pattern of the interdigestive migrating electric complex (IMEC) was observed by electromyography. The nerve regulatory mechanism in intestinal movement was investigated. The results indicated that first, the frequency of the basic electric rhythm (BER) is controlled so that a downward gradient is formed from the upper to the lower intestine, but this gradient continues to be controlled by a two-dimensional control mechanism involving parietal factors and extrinsic nerves due to transection of the intestines and damage to the extrinsic nerves in the dominant region. However, propagation of the IMEC in the small intestine appeared to be regulated by a combination of the two-dimensional control mechanism involving extrinsic and parietal nerves corresponding to the BER control mechanism. It was clear that the propagation mechanism of IMEC is related to the BER frequency, and propagation of the IMEC is downward in accordance with the frequency gradient of BER.

摘要

制备犬小肠的节段和三十维拉型肠袢,通过肌电图观察消化间期移行性复合运动(IMEC)的兴奋传播模式。研究肠道运动中的神经调节机制。结果表明,首先,基础电节律(BER)的频率受到控制,从而形成从十二指肠到回肠的向下梯度,但由于肠道横断和优势区域的外在神经损伤,这种梯度继续由涉及壁内因素和外在神经的二维控制机制控制。然而,小肠中IMEC的传播似乎受与BER控制机制相对应的涉及外在神经和壁内神经的二维控制机制的组合调节。很明显,IMEC的传播机制与BER频率相关,并且IMEC的传播根据BER的频率梯度向下进行。

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