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贝娜齐尔·纳肖努马项目(BNP)对巴基斯坦孕产妇、儿童健康及营养状况的影响评估:一项准实验研究方案

Impact assessment of Benazir Nashonuma Programme (BNP) on maternal, child health and nutritional status in Pakistan: a quasi-experimental study protocol.

作者信息

Muhammad Shah, Malik Asma Abdul, Soofi Sajid, Habib Atif, Umer Muhammad, Rizvi Arjumand, Ahmed Imran, Leroy Jef, Cousens Simon, Bhutta Zulfiqar Ahmed

机构信息

CoE in Women and Child Health, The Aga Khan University, Karachi, Pakistan.

Pediatrics and Child Health, The Aga Khan University, Karachi, Pakistan.

出版信息

BMJ Open. 2025 Jun 27;15(6):e094565. doi: 10.1136/bmjopen-2024-094565.

Abstract

INTRODUCTION

Maternal and child malnutrition is a significant public health concern in Pakistan, with 40% of children under five being stunted. In response, the Government of Pakistan initiated the Benazir Nashonuma Programme (BNP), a nutritional supplementation programme for pregnant women, mothers of children aged 0 to 23 months and children aged 6 to 24 months. This study aims to evaluate the effectiveness of the BNP in reducing childhood stunting and improving maternal and child health outcomes.

METHODS AND ANALYSIS

A quasi-experimental longitudinal study comprising baseline, midline and endline surveys will be conducted across 18 districts (9 intervention and 9 control) in Pakistan. The surveys will use a two-stage cluster sampling method to enrol 13 200 children aged 0-59 months and their mothers from the Benazir Income Support Programme households. The primary outcome of interest is the prevalence of under-five stunting. We will use a difference-in-differences approach to estimate the impact by comparing the documented changes over time between the intervention and control groups.

ETHICS AND DISSEMINATION

This study will provide critical insights into the effectiveness of the BNP in addressing childhood undernutrition in Pakistan. The findings will inform policy and programmatic decisions aimed at reducing undernutrition in resource-constrained settings. Ethical approval has been obtained from the Ethics Review Committee of Aga Khan University and the Pakistan National Bioethics Committee.

TRIAL REGISTRATION NUMBER

NCT06025786.

摘要

引言

母婴营养不良是巴基斯坦一个重大的公共卫生问题,40%的五岁以下儿童发育迟缓。作为回应,巴基斯坦政府启动了贝娜齐尔营养计划(BNP),这是一项针对孕妇、0至23个月儿童的母亲以及6至24个月儿童的营养补充计划。本研究旨在评估BNP在减少儿童发育迟缓以及改善母婴健康结果方面的有效性。

方法与分析

将在巴基斯坦的18个地区(9个干预地区和9个对照地区)开展一项包括基线调查、中期调查和终期调查的准实验纵向研究。这些调查将采用两阶段整群抽样方法,从贝娜齐尔收入支持计划家庭中招募13200名0至59个月的儿童及其母亲。主要关注的结果是五岁以下儿童发育迟缓的患病率。我们将采用差分法,通过比较干预组和对照组随时间记录的变化来估计影响。

伦理与传播

本研究将为BNP在解决巴基斯坦儿童营养不良问题方面的有效性提供关键见解。研究结果将为旨在减少资源有限环境中营养不良情况的政策和项目决策提供参考。已获得阿迦汗大学伦理审查委员会和巴基斯坦国家生物伦理委员会的伦理批准。

试验注册号

NCT06025786。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b12/12207155/5958c890e26f/bmjopen-15-6-g001.jpg

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