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无条件现金转移以减少贫困和脆弱性:对中低收入国家卫生服务利用和健康结果的影响。

Unconditional cash transfers for reducing poverty and vulnerabilities: effect on use of health services and health outcomes in low- and middle-income countries.

机构信息

Department of Public Health, University of Otago, Wellington, New Zealand.

School of Public Health, University of Alberta, Edmonton, Canada.

出版信息

Cochrane Database Syst Rev. 2022 Mar 29;3(3):CD011135. doi: 10.1002/14651858.CD011135.pub3.

Abstract

BACKGROUND

Unconditional cash transfers (UCTs; provided without obligation) for reducing poverty and vulnerabilities (e.g. orphanhood, old age, or HIV infection) are a social protection intervention addressing a key social determinant of health (income) in low- and middle-income countries (LMICs). The relative effectiveness of UCTs compared with conditional cash transfers (CCTs; provided only if recipients follow prescribed behaviours, e.g. use a health service or attend school) is unknown.

OBJECTIVES

To assess the effects of UCTs on health services use and health outcomes in children and adults in LMICs. Secondary objectives are to assess the effects of UCTs on social determinants of health and healthcare expenditure, and to compare the effects of UCTs versus CCTs.

SEARCH METHODS

For this update, we searched 15 electronic academic databases, including CENTRAL, MEDLINE and EconLit, in September 2021. We also searched four electronic grey literature databases, websites of key organisations and reference lists of previous systematic reviews, key journals and included study records.

SELECTION CRITERIA

We included both parallel-group and cluster-randomised controlled trials (C-RCTs), quasi-RCTs, cohort studies, controlled before-and-after studies (CBAs), and interrupted time series studies of UCT interventions in children (0 to 17 years) and adults (≥ 18 years) in LMICs. Comparison groups received either no UCT, a smaller UCT or a CCT. Our primary outcomes were any health services use or health outcome.

DATA COLLECTION AND ANALYSIS

Two review authors independently screened potentially relevant records for inclusion, extracted data and assessed the risk of bias. We obtained missing data from study authors if feasible. For C-RCTs, we generally calculated risk ratios for dichotomous outcomes from crude frequency measures in approximately correct analyses. Meta-analyses applied the inverse variance or Mantel-Haenszel method using a random-effects model. Where meta-analysis was impossible, we synthesised results using vote counting based on effect direction. We assessed the certainty of the evidence using GRADE.

MAIN RESULTS

We included 34 studies (25 studies of 20 C-RCTs, six CBAs, and three cohort studies) involving 1,140,385 participants (45,538 children, 1,094,847 adults) and 50,095 households in Africa, the Americas and South-East Asia in our meta-analyses and narrative syntheses. These analysed 29 independent data sets. The 24 UCTs identified, including one basic universal income intervention, were pilot or established government programmes or research experiments. The cash value was equivalent to 1.3% to 81.9% of the annualised gross domestic product per capita. All studies compared a UCT with no UCT; three studies also compared a UCT with a CCT. Most studies carried an overall high risk of bias (i.e. often selection or performance bias, or both). Most studies were funded by national governments or international organisations, or both. Throughout the review, we use the words 'probably' to indicate moderate-certainty evidence, 'may/maybe' for low-certainty evidence, and 'uncertain' for very low-certainty evidence. Health services use We assumed greater use of any health services to be beneficial. UCTs may not have impacted the likelihood of having used any health service in the previous 1 to 12 months, when participants were followed up between 12 and 24 months into the intervention (risk ratio (RR) 1.04, 95% confidence interval (CI) 1.00 to 1.09; I = 2%; 5 C-RCTs, 4972 participants; low-certainty evidence). Health outcomes At one to two years, UCTs probably led to a clinically meaningful, very large reduction in the likelihood of having had any illness in the previous two weeks to three months (RR 0.79, 95% CI 0.67 to 0.92; I = 53%; 6 C-RCTs, 9367 participants; moderate-certainty evidence). UCTs may have increased the likelihood of having been food secure over the previous month, at 13 to 36 months into the intervention (RR 1.25, 95% CI 1.09 to 1.45; I = 85%; 5 C-RCTs, 2687 participants; low-certainty evidence). UCTs may have increased participants' level of dietary diversity over the previous week, when assessed with the Household Dietary Diversity Score and followed up 24 months into the intervention (mean difference (MD) 0.59 food categories, 95% CI 0.18 to 1.01; I = 79%; 4 C-RCTs, 9347 participants; low-certainty evidence). Despite several studies providing relevant evidence, the effects of UCTs on the likelihood of being moderately stunted and on the level of depression remain uncertain. We found no study on the effect of UCTs on mortality risk. Social determinants of health UCTs probably led to a clinically meaningful, moderate increase in the likelihood of currently attending school, when assessed at 12 to 24 months into the intervention (RR 1.06, 95% CI 1.04 to 1.09; I = 0%; 8 C-RCTs, 7136 participants; moderate-certainty evidence). UCTs may have reduced the likelihood of households being extremely poor, at 12 to 36 months into the intervention (RR 0.92, 95% CI 0.87 to 0.97; I = 63%; 6 C-RCTs, 3805 participants; low-certainty evidence). The evidence was uncertain for whether UCTs impacted livestock ownership, participation in labour, and parenting quality. Healthcare expenditure Evidence from eight cluster-RCTs on healthcare expenditure was too inconsistent to be combined in a meta-analysis, but it suggested that UCTs may have increased the amount of money spent on health care at 7 to 36 months into the intervention (low-certainty evidence). Equity, harms and comparison with CCTs The effects of UCTs on health equity (or unfair and remedial health inequalities) were very uncertain. We did not identify any harms from UCTs. Three cluster-RCTs compared UCTs versus CCTs with regard to the likelihood of having used any health services or had any illness, or the level of dietary diversity, but evidence was limited to one study per outcome and was very uncertain for all three.

AUTHORS' CONCLUSIONS: This body of evidence suggests that unconditional cash transfers (UCTs) may not impact a summary measure of health service use in children and adults in LMICs. However, UCTs probably or may improve some health outcomes (i.e. the likelihood of having had any illness, the likelihood of having been food secure, and the level of dietary diversity), two social determinants of health (i.e. the likelihoods of attending school and being extremely poor), and healthcare expenditure. The evidence on the relative effectiveness of UCTs and CCTs remains very uncertain.

摘要

背景

无条件现金转移支付(UCTs;无需义务提供)可减少贫困和脆弱性(例如孤儿、老年或感染艾滋病毒),是一种针对中低收入国家(LMICs)关键社会决定因素(收入)的社会保护干预措施。与有条件现金转移支付(CCTs;仅在接受者遵守规定行为时提供,例如使用卫生服务或上学)相比,UCTs 的相对效果尚不清楚。

目的

评估 UCT 对 LMIC 中儿童和成人的卫生服务使用和健康结果的影响。次要目标是评估 UCT 对健康决定因素和医疗支出的影响,并比较 UCT 与 CCT 的效果。

检索方法

本次更新,我们于 2021 年 9 月在 15 个电子学术数据库(包括 CENTRAL、MEDLINE 和 EconLit)进行了检索,并在四个电子灰色文献数据库、关键组织的网站以及先前系统评价、主要期刊和纳入研究记录的参考文献列表中进行了检索。

选择标准

我们纳入了 UCT 干预措施在儿童(0 至 17 岁)和成人(≥18 岁)中进行的平行组和群组随机对照试验(C-RCTs)、准随机对照试验、队列研究、对照前和后研究(CBAs)以及中断时间序列研究。对照组接受无 UCT、较小的 UCT 或 CCT。我们的主要结局是任何卫生服务使用或健康结果。

数据收集和分析

两名综述作者独立筛选潜在相关记录以进行纳入、提取数据并评估偏倚风险。如果可行,我们从研究作者那里获取缺失数据。对于 C-RCTs,我们通常根据大致正确分析中未经处理的频率测量值计算二分类结局的风险比。荟萃分析采用逆方差或 Mantel-Haenszel 方法,使用随机效应模型。对于无法进行荟萃分析的情况,我们根据效果方向进行投票计数来综合结果。我们使用 GRADE 评估证据的确定性。

主要结果

我们纳入了 34 项研究(25 项研究包含 20 项 C-RCTs、6 项 CBA 和 3 项队列研究),涉及 1140385 名参与者(45538 名儿童和 1094847 名成人)和非洲、美洲和东南亚的 50095 户家庭。这些分析包括 29 个独立的数据集。确定的 24 项 UCT 包括一项基本普遍的收入干预措施,均为试点或既定政府计划或研究实验。现金价值相当于人均年化国内生产总值的 1.3%至 81.9%。所有研究均存在总体高偏倚风险(即通常存在选择或表现偏倚,或两者兼而有之)。大多数研究由国家政府或国际组织或两者共同资助。在整个综述中,我们使用“可能”表示中等确定性证据,“可能/也许”表示低确定性证据,“不确定”表示非常低确定性证据。

卫生服务使用

我们假设增加任何卫生服务的使用可能是有益的。UCTs 可能不会影响参与者在 1 至 12 个月内使用任何卫生服务的可能性,当参与者在干预 12 至 24 个月内被随访时(风险比(RR)1.04,95%置信区间(CI)1.00 至 1.09;I = 2%;5 项 C-RCTs,4972 名参与者;低确定性证据)。

健康结果

在 1 至 2 年内,UCTs 可能会显著降低参与者在前 2 至 3 个月内任何疾病的可能性(RR 0.79,95%置信区间(CI)0.67 至 0.92;I = 53%;6 项 C-RCTs,9367 名参与者;中等确定性证据)。在 13 至 36 个月的干预中,UCTs 可能会增加参与者过去一个月获得食物保障的可能性(RR 1.25,95%置信区间(CI)1.09 至 1.45;I = 85%;5 项 C-RCTs,2687 名参与者;低确定性证据)。在干预 24 个月时,UCTs 可能会增加参与者每周的饮食多样性(用家庭饮食多样性评分衡量)(MD 0.59 种食物,95%CI 0.18 至 1.01;I = 79%;4 项 C-RCTs,9347 名参与者;低确定性证据)。尽管多项研究提供了相关证据,但 UCTs 对中度发育迟缓的影响和抑郁程度的影响仍不确定。我们没有发现关于 UCTs 对死亡率影响的研究。

社会决定因素

UCTs 可能会显著增加参与者目前上学的可能性,在 12 至 24 个月的干预中评估(RR 1.06,95%置信区间(CI)1.04 至 1.09;I = 0%;8 项 C-RCTs,7136 名参与者;中等确定性证据)。UCTs 可能会降低家庭极度贫困的可能性,在 12 至 36 个月的干预中评估(RR 0.92,95%置信区间(CI)0.87 至 0.97;I = 63%;6 项 C-RCTs,3805 名参与者;低确定性证据)。证据不确定 UCTs 是否会影响牲畜所有权、参与劳动和育儿质量。

医疗支出

来自 8 项集群 RCT 的医疗支出证据不一致,无法进行荟萃分析,但表明 UCTs 可能会在 7 至 36 个月的干预中增加医疗支出(低确定性证据)。

公平性、危害和与 CCT 的比较:UCTs 对健康公平(或不公平和补救性健康不平等)的影响非常不确定。我们没有发现 UCTs 的任何危害。三项集群 RCT 比较了 UCTs 与 CCTs 在使用任何卫生服务或患病方面的效果,或饮食多样性方面的效果,但每个结果只有一项研究,所有结果的证据都非常不确定。

作者结论

本证据表明,无条件现金转移支付(UCTs)可能不会影响中低收入国家(LMICs)儿童和成人的综合卫生服务使用情况。然而,UCTs 可能会改善一些健康结果(即患病的可能性、获得食物保障的可能性和饮食多样性)、两个社会决定因素(即上学的可能性和极度贫困)以及医疗支出。UCTs 和 CCTs 的相对效果仍然非常不确定。

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