在涉及马普替林和阿米替林的疑似过量用药病例中，从分解组织中有效提取柱成分。
Effective column extraction from decomposed tissue in a suspected overdose case involving maprotiline and amitriptyline.
作者信息
Fernandez G S, Witherington T L, Stafford D T
出版信息
J Anal Toxicol. 1985 Sep-Oct;9(5):230-1. doi: 10.1093/jat/9.5.230.
PMID:4057962
Abstract
This paper describes the use of a Celite 560 column extraction technique in the initial separation of drugs from the contents of the skull of a severely decomposed body. Analysis of the extract obtained resulted in the determination of the presence of amitriptyline, and maprotiline and two of its metabolites. As a consequence, the laboratory was able to provide the medical examiner with information concerning an extremely difficult case.
摘要
本文描述了使用硅藻土560柱提取技术，从一具严重腐烂尸体的颅骨内容物中初步分离药物的过程。对所得提取物的分析确定了阿米替林、马普替林及其两种代谢物的存在。因此，实验室能够为法医提供有关这起极其棘手案件的信息。
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