Jan Yih-Kuen, Cheung W Catherine
Department of Health and Kinesiology, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
Physical Therapy Program, Northern Illinois University, DeKalb, IL, USA.
Med Gas Res. 2026 Mar 1;16(1):66-75. doi: 10.4103/mgr.MEDGASRES-D-24-00149. Epub 2025 Jun 28.
Skeletal muscle oxygenation reflects the balance between oxygen delivery from the microcirculation and oxygen consumption of the muscle cells. Oxygenation in the muscle tissue is an essential factor in muscle contractions for performing activities of daily living and exercise as well as muscle tissue viability. It is until the development of near-infrared spectroscopy for providing a noninvasive, continuous monitoring of muscle oxygenation. The principle of near-infrared spectroscopy is to use light property to assess oxygenation based on the appearance of oxygenated blood in red and deoxygenated blood in darker red to black. To date, there is no comprehensive review focusing on muscle oxygenation regulation and its applications in physical therapy and rehabilitation. The objectives of this comprehensive review are to: 1) highlight the recent technical advances in near-infrared spectroscopytechnology for rehabilitation researchers, 2) present the advances in pathophysiological research in muscle oxygenation, and 3) evaluate findings and evidence of recent physical therapy and rehabilitation studies on improving muscle oxygenation. The review also evaluates findings and evidence of aerobic exercise, resistance exercise, contrast bath therapy, wound healing, cupping therapy, stretching, and electrical stimulation on muscle oxygen in healthy adults and patients with cardiovascular diseases. The use of near-infrared spectroscopy allows the assessment of muscle oxidative metabolism for personalized rehabilitation and exercise training.
骨骼肌氧合反映了微循环的氧输送与肌肉细胞氧消耗之间的平衡。肌肉组织中的氧合是进行日常生活活动和运动以及维持肌肉组织活力的肌肉收缩中的一个重要因素。直到近红外光谱技术发展起来，才能够对肌肉氧合进行无创、连续监测。近红外光谱技术的原理是利用光的特性，根据含氧血液呈现红色以及脱氧血液呈现暗红色至黑色来评估氧合情况。迄今为止，尚无专注于肌肉氧合调节及其在物理治疗和康复中应用的全面综述。本全面综述的目的是：1）向康复研究人员突出近红外光谱技术的最新技术进展；2）介绍肌肉氧合病理生理学研究的进展；3）评估近期物理治疗和康复研究中关于改善肌肉氧合的研究结果和证据。该综述还评估了有氧运动、抗阻运动、对比浴疗法、伤口愈合、拔罐疗法、拉伸以及电刺激对健康成年人和心血管疾病患者肌肉氧合的研究结果和证据。使用近红外光谱技术能够评估肌肉氧化代谢，以进行个性化康复和运动训练。
