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心理治疗干预对子宫内膜异位症疼痛和生活质量的影响:一项系统评价和荟萃分析研究

The effect of psychotherapeutic interventions on pain and quality of life in endometriosis: a systematic review and meta-analysis study.

作者信息

Özcan Handan, Çuvadar Ayşe, Uzun Sevda

机构信息

Hamidiye Faculty of Health Sciences, University of Health Sciences, Istanbul, Turkey.

Department of Midwifery, Faculty of Health Sciences, Karabuk University, Karabuk, Turkey.

出版信息

Ir J Med Sci. 2025 Jun 28. doi: 10.1007/s11845-025-03985-6.

DOI:10.1007/s11845-025-03985-6
PMID:40580241
Abstract

AIM

This study aimed to determine the effect of psychotherapeutic interventions on pain, quality of life and health profile in women diagnosed with endometriosis.

METHODS

For this systematic review and meta-analysis study, studies were obtained by searching PubMed, Web of Science, EBSCOhost, Google Scholar, and YÖK Thesis Center databases between August and October 2024 without any year limitation. After the review, 10 studies were included in the study. The data were synthesized by meta-analysis and narrative methods.

RESULTS

In this systematic review and meta-analysis, psychotherapeutic interventions for the treatment and management of endometriosis were found to be effective on quality of life (SMD = 0.515, 95% CI = 0.035 to 0.995; Z = 2.104, I = 67.523%, p < 0.05), pain (SMD =  - 0.454, 95% CI =  - 1.600 to - 0.179; Z =  - 1.566, I = 84.463, p > 0.05), and health profile (SMD = 0.041, 95% CI =  - 0.363 to 0.281; Z =  - 0.250759, I = 56.876%, p > 0.05). In subgroup analyses, it was determined that the types of psychotherapeutic interventions were not effective, but the number of sessions was effective.

CONCLUSION

Psychotherapeutic interventions to reduce symptoms in endometriosis are effective in improving quality of life but not pain and health profile.

摘要

目的

本研究旨在确定心理治疗干预对被诊断为子宫内膜异位症的女性的疼痛、生活质量和健康状况的影响。

方法

对于这项系统评价和荟萃分析研究,通过检索2024年8月至10月期间的PubMed、科学网、EBSCOhost、谷歌学术和土耳其国家高等教育委员会论文中心数据库获取研究,无年份限制。经过筛选,10项研究被纳入本研究。数据通过荟萃分析和叙述性方法进行综合。

结果

在这项系统评价和荟萃分析中,发现用于治疗和管理子宫内膜异位症的心理治疗干预对生活质量有效(标准化均数差[SMD]=0.515,95%置信区间[CI]=0.035至0.995;Z=2.104,I²=67.523%,P<0.05),对疼痛有效(SMD=-0.454,95%CI=-1.600至-0.179;Z=-1.566,I²=84.463,P>0.05),对健康状况有效(SMD=0.041,95%CI=-0.363至0.281;Z=-0.250759,I²=56.876%,P>0.05)。在亚组分析中,确定心理治疗干预的类型无效,但治疗疗程数有效。

结论

减轻子宫内膜异位症症状的心理治疗干预在改善生活质量方面有效,但在减轻疼痛和改善健康状况方面无效。

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本文引用的文献

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Diet in Prevention and Treatment of Endometriosis: Current State of Knowledge.饮食在子宫内膜异位症防治中的应用:当前知识现状
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Mindfulness intervention effect on endometriosis-related pain dimensions and its mediator role on stress and vitality: a path analysis approach.正念干预对子宫内膜异位症相关疼痛维度的影响及其对压力和活力的中介作用:路径分析方法。
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Effectiveness of a Manual Therapy Protocol in Women with Pelvic Pain Due to Endometriosis: A Randomized Clinical Trial.
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Transcranial direct current stimulation to reduce chronic pelvic pain in endometriosis: phase II randomized controlled clinical trial.经颅直流电刺激治疗子宫内膜异位症慢性盆腔痛的随机对照Ⅱ期临床试验
Pain Med. 2023 Jul 5;24(7):809-817. doi: 10.1093/pm/pnad031.
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Psychological interventions improve quality of life despite persistent pain in endometriosis: results of a 3-armed randomized controlled trial.心理干预可改善子宫内膜异位症患者的生活质量,尽管其持续存在疼痛:一项三臂随机对照试验的结果。
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Benefits of physical therapy in improving quality of life and pain associated with endometriosis: A systematic review and meta-analysis.物理治疗对改善子宫内膜异位症相关生活质量和疼痛的益处:系统评价和荟萃分析。
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The role of acupuncture in the treatment of women with pain in endometriosis: A protocol for systematic review and meta-analysis.针灸治疗子宫内膜异位症相关疼痛的作用:系统评价和荟萃分析方案。
Medicine (Baltimore). 2021 Dec 10;100(49):e27582. doi: 10.1097/MD.0000000000027582.
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Effect of physical activity and exercise on endometriosis-associated symptoms: a systematic review.体力活动和锻炼对子宫内膜异位症相关症状的影响:系统评价。
BMC Womens Health. 2021 Oct 9;21(1):355. doi: 10.1186/s12905-021-01500-4.
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Hum Reprod Open. 2019 Jun 12;2019(3):hoz009. doi: 10.1093/hropen/hoz009. eCollection 2019.