• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一例伴有脾肿大的胃肠道出血的独特病例。

A unique case of gastrointestinal bleeding with splenomegaly.

作者信息

Gan Can, Tang Shihang

机构信息

Department of Gastroenterology, West China Hospital, Sichuan University, Chengdu, China.

Department of Gastroenterology, Chongqing University Cancer Hospital, China.

出版信息

SAGE Open Med Case Rep. 2025 Jun 27;13:2050313X251351454. doi: 10.1177/2050313X251351454. eCollection 2025.

DOI:10.1177/2050313X251351454
PMID:40584539
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12205179/
Abstract

We present the case of a 61-year-old man with a 30-year history of iron-deficiency anemia and recurrent gastrointestinal bleeding, accompanied by splenomegaly and hypersplenism. Despite multiple endoscopy and imaging examinations, the source of bleeding remained elusive. The patient ultimately underwent exploratory laparotomy with splenectomy, which revealed a Meckel's diverticulum with stale hemorrhage, along with congestive changes in the spleen. Following surgery, the patient experienced a complete resolution of symptoms with normalization of hematological parameters. This case highlights Meckel's diverticulum as a rare cause of obscure gastrointestinal bleeding, with the unique presentation of splenomegaly due to extramedullary hematopoiesis.

摘要

我们报告了一例61岁男性患者,有30年缺铁性贫血和反复胃肠道出血病史,伴有脾肿大和脾功能亢进。尽管进行了多次内镜检查和影像学检查,但出血来源仍不明确。患者最终接受了剖腹探查术并脾切除术,术中发现一个有陈旧性出血的梅克尔憩室,同时脾脏有充血性改变。术后,患者症状完全缓解,血液学参数恢复正常。该病例突出了梅克尔憩室作为隐匿性胃肠道出血的罕见原因,以及因髓外造血导致脾肿大的独特表现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f2c/12205179/83ee67a5ad5c/10.1177_2050313X251351454-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f2c/12205179/83ee67a5ad5c/10.1177_2050313X251351454-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f2c/12205179/83ee67a5ad5c/10.1177_2050313X251351454-fig1.jpg

相似文献

1
A unique case of gastrointestinal bleeding with splenomegaly.一例伴有脾肿大的胃肠道出血的独特病例。
SAGE Open Med Case Rep. 2025 Jun 27;13:2050313X251351454. doi: 10.1177/2050313X251351454. eCollection 2025.
2
Meckel's diverticulum as a lead point for intussusception in the first day of life: A case report of neonatal perforation.梅克尔憩室作为出生首日肠套叠的起始点:新生儿穿孔病例报告
Int J Surg Case Rep. 2025 Jun 19;133:111548. doi: 10.1016/j.ijscr.2025.111548.
3
Coexistence of cecal duplication cyst and Meckel's diverticulum presenting as intussusception in a malnourished child a case report with literature review.盲肠重复囊肿与梅克尔憩室并存致营养不良儿童肠套叠:一例报告并文献复习
BMC Pediatr. 2025 Jul 1;25(1):479. doi: 10.1186/s12887-025-05823-1.
4
Systematic review of epidemiology, presentation, and management of Meckel's diverticulum in the 21st century.21世纪梅克尔憩室的流行病学、临床表现及治疗的系统评价
Medicine (Baltimore). 2018 Aug;97(35):e12154. doi: 10.1097/MD.0000000000012154.
5
Severe Rectal Hemorrhage in Adolescents: An Unusual Presentation of Meckel's Diverticulum.青少年严重直肠出血:梅克尔憩室的一种不寻常表现。
Cureus. 2025 May 22;17(5):e84601. doi: 10.7759/cureus.84601. eCollection 2025 May.
6
Perforated Meckel's Diverticulum in an Infant: A Case Report and Review of the Literature.婴儿梅克尔憩室穿孔:一例病例报告及文献复习
Cureus. 2025 May 29;17(5):e85066. doi: 10.7759/cureus.85066. eCollection 2025 May.
7
Drugs to reduce bleeding and transfusion in major open vascular or endovascular surgery: a systematic review and network meta-analysis.减少大型开放性血管或血管内手术中出血和输血的药物:系统评价和网络荟萃分析。
Cochrane Database Syst Rev. 2023 Feb 17;2(2):CD013649. doi: 10.1002/14651858.CD013649.pub2.
8
Gaucher Disease戈谢病
9
Fasting for haemostasis in children with gastrointestinal bleeding.禁食用于小儿胃肠道出血的止血治疗。
Cochrane Database Syst Rev. 2016 May 19;2016(5):CD010714. doi: 10.1002/14651858.CD010714.pub2.
10
Splenectomy for people with thalassaemia major or intermedia.为重型或中间型地中海贫血患者进行脾切除术。
Cochrane Database Syst Rev. 2016 Jun 14(6):CD010517. doi: 10.1002/14651858.CD010517.pub2.

本文引用的文献

1
Italian guidelines for the diagnosis and management of colonic diverticulosis and diverticular disease.意大利结肠憩室病和憩室疾病的诊断和管理指南。
Dig Liver Dis. 2024 Dec;56(12):1989-2003. doi: 10.1016/j.dld.2024.06.031. Epub 2024 Jul 14.
2
Current Management of Diverticulitis.目前对憩室炎的处理。
Surg Clin North Am. 2024 Jun;104(3):529-543. doi: 10.1016/j.suc.2023.12.001. Epub 2023 Dec 22.
3
Obscure-overt gastrointestinal bleeding: a review.隐匿性-显性胃肠道出血:综述。
Pol Arch Intern Med. 2022 May 30;132(5). doi: 10.20452/pamw.16253.
4
A case of obscure gastrointestinal bleeding in a 18-year-old woman.
Ann Ital Chir. 2014 Mar 7;85:S2239253X14022257.
5
Meckel's diverticulum and the eponymous legend. Meckel 憩室和同名传说。
J Trauma Acute Care Surg. 2019 Aug;87(2):451-455. doi: 10.1097/TA.0000000000002300.
6
Meckel's diverticulum diagnosis by video capsule endoscopy: A case report and review of literature.通过视频胶囊内镜诊断梅克尔憩室:一例病例报告及文献复习
World J Clin Cases. 2018 Nov 26;6(14):791-799. doi: 10.12998/wjcc.v6.i14.791.
7
Systematic review of epidemiology, presentation, and management of Meckel's diverticulum in the 21st century.21世纪梅克尔憩室的流行病学、临床表现及治疗的系统评价
Medicine (Baltimore). 2018 Aug;97(35):e12154. doi: 10.1097/MD.0000000000012154.
8
Meckel's diverticulum in the adult.成人的梅克尔憩室。
J Visc Surg. 2017 Sep;154(4):253-259. doi: 10.1016/j.jviscsurg.2017.06.006. Epub 2017 Jul 9.
9
Diverticular Disease: An Update on Pathogenesis and Management.憩室病:发病机制和治疗的最新进展。
Gut Liver. 2018 Mar 15;12(2):125-132. doi: 10.5009/gnl16552.
10
Detection of splenomegaly on Meckel's diverticulum scan.
Clin Nucl Med. 2009 Mar;34(3):191-2. doi: 10.1097/RLU.0b013e31819672a7.