Department of Medical-Surgical Sciences and Translational Medicine, Sant'Andrea Hospital, Sapienza University of Rome, Rome, Italy.
Gastroenterology and Endoscopy Unit, "Sant'Anna e San Sebastiano" Hospital Caserta, 81100 Caserta, Italy.
Dig Liver Dis. 2024 Dec;56(12):1989-2003. doi: 10.1016/j.dld.2024.06.031. Epub 2024 Jul 14.
Colonic diverticulosis and diverticular disease are among the most common gastrointestinal disorders encountered in clinical practice. These Italian guidelines focus on the diagnosis and management of diverticulosis and diverticular disease in the adult population, providing practical and evidence-based recommendations for clinicians. Experts from five Italian scientific societies, constituting a multidisciplinary panel, conducted a comprehensive review of meta-analyses, systematic reviews, randomised controlled trials, and observational studies to formulate 14 PICO questions. The assessment of the quality of the evidence and the formulation of the recommendations were carried out using an adaptation of the GRADE methodology. The guidelines covered the following topics: i) Management of diverticulosis; ii) Symptomatic uncomplicated diverticular disease: diagnosis and treatment; iii) Acute diverticulitis: diagnosis and treatment; iv) Management of diverticular disease complications; v) Prevention of recurrent acute diverticulitis; vi) Interventional management of diverticular disease.
结肠憩室病和憩室疾病是临床实践中最常见的胃肠道疾病之一。这些意大利指南侧重于成年人群中憩室病和憩室疾病的诊断和管理，为临床医生提供实用和基于证据的建议。来自五个意大利科学学会的专家组成一个多学科小组，对荟萃分析、系统评价、随机对照试验和观察性研究进行了全面审查，制定了 14 个 PICO 问题。使用 GRADE 方法的改编版评估证据质量并制定建议。指南涵盖了以下主题：i）憩室病的管理；ii）有症状的单纯性憩室疾病：诊断和治疗；iii）急性憩室炎：诊断和治疗；iv）憩室疾病并发症的管理；v）预防复发性急性憩室炎；vi）憩室疾病的介入治疗。
