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睾丸旁横纹肌肉瘤治疗的病例报告:睾丸切除术、放疗前睾丸转位及放疗后睾丸固定术。

A case report of paratesticular rhabdomyosarcoma management: Orchiectomy, pre-radiation testicular transposition, and post-radiation orchiopexy.

作者信息

Sturgis Morgan R, Rosen Jennifer, Gong Edward M, Johnson Emilie K

机构信息

Department of Urology, Rush University Medical Center, USA.

Division of Urology, Ann & Robert H. Lurie Children's Hospital of Chicago, USA.

出版信息

Urol Case Rep. 2025 Jun 6;61:103086. doi: 10.1016/j.eucr.2025.103086. eCollection 2025 Jul.

DOI:10.1016/j.eucr.2025.103086
PMID:40584998
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12205670/
Abstract

Paratesticular rhabdomyosarcoma is a rare malignancy with favorable prognosis when treated with radical inguinal orchiectomy ± chemotherapy and radiation for patients with advanced disease. When scrotal radiation is indicated, testicular preservation is a pivotal consideration. A widely accepted recommendation is temporary transposition of the remaining testicle to a thigh pouch prior to initiation of radiation. Here, we describe the clinical course of a young patient with paratesticular rhabdomyosarcoma and our unique operative approach using a Bianchi incision during thigh pouch creation to allow for groin preservation followed by a staged inguinal approach for post-radiation orchiopexy.

摘要

睾丸旁横纹肌肉瘤是一种罕见的恶性肿瘤,对于晚期疾病患者,采用根治性腹股沟睾丸切除术±化疗和放疗,预后良好。当需要进行阴囊放疗时,保留睾丸是一个关键考虑因素。一个广泛接受的建议是在开始放疗前将剩余睾丸临时转移至大腿袋。在此,我们描述了一名年轻睾丸旁横纹肌肉瘤患者的临床病程,以及我们独特的手术方法,即在创建大腿袋时采用比安基切口以保留腹股沟,随后采用分期腹股沟入路进行放疗后睾丸固定术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5827/12205670/7448995f254a/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5827/12205670/8b75e16bb90f/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5827/12205670/9039712f18bf/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5827/12205670/ee3203a897e1/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5827/12205670/7448995f254a/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5827/12205670/8b75e16bb90f/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5827/12205670/9039712f18bf/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5827/12205670/ee3203a897e1/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5827/12205670/7448995f254a/gr4.jpg

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本文引用的文献

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Fasciocutaneous Flap Perineal Closure with Testicular Thigh Pouch for Scrotal Defects: Surgical Technique and Initial Experience.筋膜皮瓣会阴部闭合联合股前阴囊袋治疗阴囊缺损:手术技术与初步经验。
Urology. 2023 Dec;182:231-238. doi: 10.1016/j.urology.2023.07.039. Epub 2023 Sep 13.
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Surgical management of paratesticular rhabdomyosarcoma: A consensus opinion from the Children's Oncology Group, European paediatric Soft tissue sarcoma Study Group, and the Cooperative Weichteilsarkom Studiengruppe.
睾丸旁横纹肌肉瘤的外科治疗:来自儿童肿瘤学组、欧洲儿科软组织肉瘤研究组和软组织肉瘤合作研究组的共识意见。
Pediatr Blood Cancer. 2021 Apr;68(4):e28938. doi: 10.1002/pbc.28938. Epub 2021 Feb 1.
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Testicular transposition in children before scrotal external radiotherapy.儿童阴囊外放射治疗前的睾丸移位。
Pediatr Blood Cancer. 2020 Sep;67(9):e28526. doi: 10.1002/pbc.28526. Epub 2020 Jul 2.
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Impact of local control and surgical lymph node evaluation in localized paratesticular rhabdomyosarcoma: A report from the Children's Oncology Group Soft Tissue Sarcoma Committee.局部控制和外科淋巴结评估对局限性腹膜后横纹肌肉瘤的影响:来自儿童肿瘤学组软组织肉瘤委员会的报告。
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Recent Developments in Radiotherapy.放射治疗的最新进展
N Engl J Med. 2017 Sep 14;377(11):1065-1075. doi: 10.1056/NEJMra1608986.
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Paratesticular rhabdomyosarcoma: Importance of initial therapy.睾丸旁横纹肌肉瘤:初始治疗的重要性。
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Current management of paratesticular rhabdomyosarcoma.睾丸旁横纹肌肉瘤的当前管理
Urol Oncol. 2016 Feb;34(2):84-92. doi: 10.1016/j.urolonc.2015.10.004. Epub 2015 Nov 11.
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Surgical repositioning of the contralateral testicle before irradiation of a paratesticular rhabdomyosarcoma for preservation of hormone production.在对睾丸旁横纹肌肉瘤进行放射治疗前,对侧睾丸的手术复位以保留激素分泌。
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