Radiation Oncology Department, Centre Léon Bérard, Lyon, France.
Reproductive Medicine Department, Hospices Civils de Lyon, Lyon, France.
Pediatr Blood Cancer. 2020 Sep;67(9):e28526. doi: 10.1002/pbc.28526. Epub 2020 Jul 2.
Testicular transposition (TT) before scrotal external radiotherapy (RT) is poorly reported in children with cancer, with only rare case reports published. TT surgical techniques, dosimetric parameters, and testicular functions are retrospectively reported in 12 children, median age 12.8 years, after scrotal RT for sarcomas. TT has low morbidity and allows a dramatic RT dose decrease in the healthy testicle. Endocrine functions seem preserved while more follow-up is needed to assess fertility. Though a rare situation, TT should be discussed in children and young adult cases when a scrotal high-dose RT is needed.
睾丸转位（TT）在接受阴囊外放射治疗（RT）的癌症儿童中报道较少，仅有少数病例报告。我们回顾性报告了 12 例接受肉瘤阴囊 RT 治疗后的儿童的 TT 手术技术、剂量学参数和睾丸功能，中位年龄为 12.8 岁。TT 具有较低的发病率，并可显著降低健康睾丸的 RT 剂量。尽管需要更多的随访来评估生育能力，但内分泌功能似乎得到了保留。虽然这是一种罕见的情况，但当需要阴囊高剂量 RT 时，应在儿童和青年病例中讨论 TT。
