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18F-氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描(FDG PET-CT)心脏炎症检查方案在结核性心包炎诊断及疗效评估中的意义:病例报告

The significance of cardiac inflammatory protocol of FDG PET-CT in the diagnosis and response assessment of tuberculous pericarditis: A case report.

作者信息

Dhayalan Kabilash, Goyal Harish, Halanaik Dhanapathi, Ahamed Shaheer

机构信息

Department of Nuclear Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.

Department of Cardiology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.

出版信息

Asia Ocean J Nucl Med Biol. 2025;13(2):195-197. doi: 10.22038/aojnmb.2025.80912.1580.

Abstract

Tuberculous pericarditis (TBP) is a rare but potentially life-threatening manifestation of tuberculosis, often presenting with nonspecific symptoms and varied clinical features. The disease is characterised by inflammation of the pericardium due to mycobacterium tuberculosis, leading to complications such as effusion, tamponade, and, in chronic cases, constrictive pericarditis. TBP is associated with high mortality, particularly if not promptly diagnosed and treated. F-fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET-CT) has proven invaluable in diagnosing and managing TBP. This imaging modality allows for precise inflammatory activity localisation and differentiates TBP from other causes of pericardial disease. Additionally, the cardiac inflammation protocol of FDG PET-CT enhances imaging accuracy by suppressing the normal physiological FDG uptake in the myocardium. In this case report, we highlight the pivotal role of the cardiac inflammation protocol of FDG PET-CT in both the initial diagnosis and subsequent response assessment of TBP, underscoring its importance in clinical practice.

摘要

结核性心包炎(TBP)是一种罕见但可能危及生命的结核病表现形式,常表现为非特异性症状和多样的临床特征。该疾病的特点是由结核分枝杆菌引起心包炎症,导致诸如积液、心包填塞等并发症,在慢性病例中还会导致缩窄性心包炎。TBP与高死亡率相关,尤其是在未及时诊断和治疗的情况下。氟脱氧葡萄糖正电子发射断层扫描-计算机断层扫描(FDG PET-CT)已被证明在TBP的诊断和管理中具有重要价值。这种成像方式能够精确地定位炎症活动,并将TBP与心包疾病的其他病因区分开来。此外,FDG PET-CT的心脏炎症检查方案通过抑制心肌正常的生理性FDG摄取来提高成像准确性。在本病例报告中,我们强调了FDG PET-CT的心脏炎症检查方案在TBP的初始诊断和后续反应评估中的关键作用,突显了其在临床实践中的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b61/12205121/0447fc7523ee/AOJNMB-13-195-g001.jpg

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