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对于经阴道宫颈环扎失败的情况,采用孕前经腹宫颈峡部环扎术联合子宫腺肌病切除术。

Adenomyomectomy with preconceptional transabdominal cervicoisthmic cerclage for transvaginal cerclage failure.

作者信息

Lee Kyong-No, Park So-Yoon, Son Ga-Hyun, Lee Keun-Young

机构信息

Department of Obstetrics and Gynecology, Chungnam National University School of Medicine, Chungnam National University Hospital, Daejeon, Republic of Korea.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Hallym University College of Medicine, Kangnam Sacred Heart Hospital, Seoul, Republic of Korea.

出版信息

Front Surg. 2025 Jun 13;12:1484120. doi: 10.3389/fsurg.2025.1484120. eCollection 2025.

DOI:10.3389/fsurg.2025.1484120
PMID:40585482
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12202643/
Abstract

BACKGROUND

Despite evidence of adverse pregnancy outcomes associated with adenomyosis, there are no established strategies for risk assessment, stratification, or prevention of these potential complications. This study aimed to describe and evaluate the technique of adenomyomectomy with preconceptional transabdominal cervicoisthmic cerclage (TCIC) in high-risk women with an unfavorable history of previous preterm birth and/or second trimester miscarriage after transvaginal cerclage.

METHODS

Eligible patients had adenomyosis, confirmed by ultrasound or biopsy, and a history of second trimester miscarriages or preterm deliveries before 28 weeks despite transvaginal cerclage. All patients underwent adenomyomectomy followed by preconceptional placement of TCIC. Their obstetric and gynecologic histories, surgical outcomes, and pregnancy courses were retrospectively reviewed. Of the 85 patients who underwent this procedure at our facility over a 10-year period, we report the outcomes of 17 patients with antenatal care and delivery records available at our hospital.

RESULTS

Seventeen patients were included in the final analysis. Only one patient delivered before 34 weeks, and six between 34 and 37 weeks. One patient had three successful pregnancies following the procedure.

CONCLUSIONS

Adenomyomectomy with preconceptional TCIC may be a viable treatment option for patients with adenomyosis who wish to have a successful pregnancy after a previous preterm delivery or miscarriage.

摘要

背景

尽管有证据表明子宫腺肌病与不良妊娠结局相关,但对于这些潜在并发症的风险评估、分层或预防,尚无既定策略。本研究旨在描述和评估在有既往早产和/或经阴道宫颈环扎术后孕中期流产不良病史的高危女性中,孕前经腹宫颈峡部环扎术(TCIC)联合子宫腺肌病切除术的技术。

方法

符合条件的患者经超声或活检确诊为子宫腺肌病,且尽管接受了经阴道宫颈环扎术,但仍有孕中期流产或28周前早产史。所有患者均接受子宫腺肌病切除术,随后进行孕前TCIC放置。对她们的妇产科病史、手术结局和妊娠过程进行回顾性分析。在我们机构10年间接受该手术的85例患者中,我们报告了17例在我院有产前检查和分娩记录患者的结局。

结果

17例患者纳入最终分析。仅1例患者在34周前分娩,6例在34至37周之间分娩。1例患者术后有3次成功妊娠。

结论

对于既往有早产或流产史且希望成功妊娠的子宫腺肌病患者,孕前TCIC联合子宫腺肌病切除术可能是一种可行的治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7d9/12202643/82fc3c0281cd/fsurg-12-1484120-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7d9/12202643/52052fa24de7/fsurg-12-1484120-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7d9/12202643/89416d8cda30/fsurg-12-1484120-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7d9/12202643/e935e9b7700d/fsurg-12-1484120-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7d9/12202643/1aa4d3de0502/fsurg-12-1484120-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7d9/12202643/82fc3c0281cd/fsurg-12-1484120-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7d9/12202643/52052fa24de7/fsurg-12-1484120-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7d9/12202643/89416d8cda30/fsurg-12-1484120-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7d9/12202643/e935e9b7700d/fsurg-12-1484120-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7d9/12202643/1aa4d3de0502/fsurg-12-1484120-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7d9/12202643/82fc3c0281cd/fsurg-12-1484120-g005.jpg

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本文引用的文献

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Clinical characteristics and outcomes of women with adenomyosis pain during pregnancy: a retrospective study.妊娠合并子宫腺肌病疼痛患者的临床特征及结局:一项回顾性研究。
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Increased risk of placenta previa and preterm birth in pregnant women with endometriosis/adenomyosis: A propensity-score matching analysis of a nationwide perinatal database in Japan.子宫内膜异位症/子宫腺肌病孕妇胎盘前置和早产风险增加:日本全国围产儿数据库的倾向评分匹配分析。
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Differences in the incidence of obstetric complications depending on the extent and location of adenomyosis lesions.
根据子宫腺肌病病变的范围和位置不同,产科并发症的发生率存在差异。
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Possible risks and benefits of adenomyomectomy on pregnancy outcomes: a retrospective analysis.子宫腺肌瘤切除术对妊娠结局的潜在风险和益处:一项回顾性分析。
AJOG Glob Rep. 2023 Sep 1;3(4):100265. doi: 10.1016/j.xagr.2023.100265. eCollection 2023 Nov.
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The association between uterine adenomyosis and adverse obstetric outcomes: A propensity score-matched analysis.子宫腺肌病与不良产科结局的关联:倾向评分匹配分析。
Acta Obstet Gynecol Scand. 2023 Jul;102(7):833-842. doi: 10.1111/aogs.14581. Epub 2023 Apr 23.
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Clinical efficacy of a novel method of fertility-preserving adenomyomectomy in infertile women with diffuse adenomyosis.一种新的保留生育功能的子宫腺肌病切除术治疗弥漫性子宫腺肌病不孕妇女的临床疗效。
Medicine (Baltimore). 2023 Mar 31;102(13):e33266. doi: 10.1097/MD.0000000000033266.
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The ADENO study: ADenomyosis and its Effect on Neonatal and Obstetric outcomes: a retrospective population-based study.ADENO 研究:子宫腺肌病及其对新生儿和产科结局的影响:一项基于人群的回顾性研究。
Am J Obstet Gynecol. 2023 Jul;229(1):49.e1-49.e12. doi: 10.1016/j.ajog.2022.12.013. Epub 2022 Dec 17.
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Am J Obstet Gynecol MFM. 2023 Jan;5(1):100757. doi: 10.1016/j.ajogmf.2022.100757. Epub 2022 Sep 28.
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Long-Term Pregnancy Outcomes of Patients with Diffuse Adenomyosis after Double-Flap Adenomyomectomy.双瓣腺肌病切除术治疗弥漫性子宫腺肌病患者的长期妊娠结局
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