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评估超声检查在40岁以下女性乳腺肿块管理中的准确性及活检必要性

Assessing the Accuracy of Ultrasonography and Biopsy Necessity in the Management of Breast Lumps in Women Less than 40 Years.

作者信息

Itanyi Ukamaka Dorothy, Chukwuegbo James Nwabueze, Okafor Ugochukwu Egbunike, Richard Samuel Kelechi, Yawe King-David Terna

机构信息

Department of Radiology, University of Abuja, Gwagwalada, FCT, Nigeria.

Breast and Endocrine Unit, Department of Surgery, University of Abuja, Gwagwalada, FCT, Nigeria.

出版信息

J West Afr Coll Surg. 2025 Jul-Sep;15(3):275-281. doi: 10.4103/jwas.jwas_54_24. Epub 2024 Jul 18.

Abstract

BACKGROUND

Following recommended guidelines, palpable breast lumps in young women should be subjected to clinical-radiologic evaluation and tissue diagnosis where necessary. However, in our local practice, most benign breast lumps are also subjected to excision biopsy. Ultrasonography is the modality of choice in the evaluation of palpable breast lumps in young women.

AIM

This study aims to determine the accuracy of ultrasonography and the necessity of tissue biopsy in the management of palpable breast lumps in women less than 40 years of age and to determine lesions that can safely be managed conservatively based on histological diagnosis.

MATERIALS AND METHODS

This was a prospective cross-sectional study of 87 adult females who had breast US and biopsy for palpable breast lumps in a tertiary healthcare center over a period of 10 months (July 2020-May 2021).

RESULTS

The age range of the women was 18-39 years (mean 27.9 ± 7.09 years).Benign lesions were noted in 86.2% of patients. No malignancy was detected in women < 25 years. Ultrasonography had sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of 100%, 93.4%, 70.6%, 100%, and 94.3%, respectively, in differentiating benign from malignant breast lumps following tissue diagnosis.

CONCLUSION

Ultrasonography and tissue biopsy are vital in the evaluation of breast lumps in women less than 40 years of age. Most (86.2%) of the lumps were benign, and no malignancy was detected in women < 25 years. The high accuracy of ultrasonography in distinguishing benign from malignant lesions suggests the need for conservative management of benign lumps in young women.

摘要

背景

遵循推荐指南,年轻女性可触及的乳腺肿块在必要时应接受临床放射学评估和组织诊断。然而,在我们当地的实际操作中,大多数良性乳腺肿块也会接受切除活检。超声检查是评估年轻女性可触及乳腺肿块的首选方式。

目的

本研究旨在确定超声检查的准确性以及组织活检在40岁以下女性可触及乳腺肿块管理中的必要性,并根据组织学诊断确定可安全进行保守治疗的病变。

材料与方法

这是一项前瞻性横断面研究,在一家三级医疗中心对87名成年女性进行了为期10个月(2020年7月至2021年5月)的乳腺超声检查和可触及乳腺肿块活检。

结果

女性年龄范围为18 - 39岁(平均27.9 ± 7.09岁)。86.2%的患者发现良性病变。25岁以下女性未检测到恶性肿瘤。在组织诊断后区分良性和恶性乳腺肿块时,超声检查的敏感性、特异性、阳性预测值、阴性预测值和准确性分别为100%、93.4%、70.6%、100%和94.3%。

结论

超声检查和组织活检在评估40岁以下女性乳腺肿块中至关重要。大多数(86.2%)肿块为良性,25岁以下女性未检测到恶性肿瘤。超声检查在区分良性和恶性病变方面的高准确性表明年轻女性良性肿块需要保守治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fba/12200790/e05a70089b63/JWACS-15-275-g001.jpg

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