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Clinical significance of IgM mesangial deposits in the nephrotic syndrome.

作者信息

Gonzalo A, Mampaso F, Gallego N, Quereda C, Fierro C, Ortuño J

出版信息

Nephron. 1985;41(3):246-9. doi: 10.1159/000183591.

DOI:10.1159/000183591
PMID:4058625
Abstract

We have studied 32 patients with idiopathic nephrotic syndrome aged from 3 to 59 years. The clinical course of 20 patients with IgM mesangial deposits was compared with that of 12 patients without glomerular immune deposits. The presence of IgM deposits seems to be unrelated to any particular clinical onset, histological pattern on light microscopy, therapy response, or clinical course in our relatively short follow-up. The conclusion from this study is that IgM mesangial deposition is not a marker for response to therapy in patients with idiopathic nephrotic syndrome.

摘要

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1
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引用本文的文献

1
The impact of IgM deposits on the outcome of Nephrotic syndrome in children.IgM沉积物对儿童肾病综合征预后的影响。
BMC Nephrol. 2017 Aug 3;18(1):260. doi: 10.1186/s12882-017-0674-7.
2
The natural history of immunoglobulin M nephropathy in adults.成人免疫球蛋白M肾病的自然病程。
Nephrol Dial Transplant. 2017 May 1;32(5):823-829. doi: 10.1093/ndt/gfw063.
3
Protracted remission of proteinuria after combined therapy with plasmapheresis and anti-CD20 antibodies/cyclophosphamide in a child with oligoclonal IgM and glomerulosclerosis.
Pediatr Nephrol. 2007 Nov;22(11):1953-6. doi: 10.1007/s00467-007-0550-y. Epub 2007 Jul 28.
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Immunopathological findings in idiopathic nephrosis: clinical significance of glomerular "immune deposits".特发性肾病的免疫病理学发现:肾小球“免疫沉积物”的临床意义
Pediatr Nephrol. 1988 Oct;2(4):402-8. doi: 10.1007/BF00853431.